Evidence map›Paper›PMID 41530635›Full record

ArticleCardiovascular engineering and technology2026

A Multi-Surface Microelectrode Catheter for Targeted Energy Delivery in Cardiac Radiofrequency Ablation: A Proof of Concept Based on Computational Simulation.

Yuqi Wu, Xingkai Ji, Tong Ren, Xiaomei Wu, Shengjie Yan

Abstract read
PubMed Publisher
In one paragraph

Article in Cardiovascular engineering and technology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yuqi WuCollege of Biomedical Engineering, Fudan University, Shanghai, 200433, China.
Xingkai JiCollege of Biomedical Engineering, Fudan University, Shanghai, 200433, China.
Tong RenCollege of Biomedical Engineering, Fudan University, Shanghai, 200433, China.
Xiaomei WuCollege of Biomedical Engineering, Fudan University, Shanghai, 200433, China.
Shengjie YanCollege of Biomedical Engineering, Fudan University, Shanghai, 200433, China. sjyan@fudan.edu.cn.ORCID 0000-0001-8479-4423

Funding

National Key Research and Development Program of China 2022YFC2404904
6 · The paper itself

Abstract

purposeInefficient energy delivery to blood remains a primary challenge in cardiac radiofrequency ablation (RFA), limiting procedural efficacy. This paper introduces and computationally validates a novel multi-surface microelectrode catheter (MSMC) designed to enhance targeted energy delivery and improve overall procedural efficiency.

methodsA 3D multiphysics computational model coupling electrical, thermal, fluid-dynamic, and mechanical fields was developed to simulate RFA. The performance of the MSMC was systematically compared against a traditional catheter by analyzing its energy distribution and thermal lesion characteristics under both standard (10-18 W vs. 30 W) and high-power short-duration (25 W vs. 60 W) protocols, assessing the impact of varying catheter angles (vertical, 45°, and parallel), and exploring its potential for real-time lesion monitoring via impedance analysis.

resultsThe MSMC directed over 75% of its energy to the myocardium, a threefold improvement over the traditional catheter (~22%), allowing the creation of comparable lesions with 40% less power. The design demonstrated high stability across different orientations. Furthermore, analysis of its impedance characteristics via Cole-Cole plots revealed a greater sensitivity for real-time lesion monitoring compared to the traditional catheter.

conclusionsThe MSMC's design, which synergizes a multi-surface electrode structure with a contact-based discharge strategy, enables more efficient and predictable lesion formation. This computational proof-of-concept study confirms its potential to improve the safety, efficacy, and real-time control of RFA procedures, offering a promising pathway for the development of next-generation therapeutic devices.

Indexed as

Cardiac CathetersCatheter AblationComputer SimulationModels, CardiovascularElectric ImpedanceEquipment DesignHumansMicroelectrodesProof of Concept StudyTime FactorsCole-Cole plotComputational simulationEnergy transfer efficiencyImpedance-based monitoringMulti-surface microelectrode catheterRadiofrequency ablation

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.