ArticleJournal of the Association for Research in Otolaryngology : JARO2026
Differentiating Causes of Post-Surgical Conductive Hearing Loss with Optical Coherence Tomography Vibrometry.
Article in Journal of the Association for Research in Otolaryngology : JARO, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeTo evaluate whether optical coherence tomography (OCT) vibrometry can differentiate causes of conductive hearing loss (CHL) following ossiculoplasty, specifically distinguishing among effusion, soft-tissue fixation, and prosthesis disconnection.
methodsWe simulated three post-surgical CHL conditions, effusion, soft-tissue fixation, and prosthesis disconnection, in a cadaveric temporal bone model (N = 10 per condition), with a partial ossicular replacement prosthesis (PORP) and cartilage graft implanted via a retrotympanic approach. A custom-built swept-source middle-ear OCT system (λ
resultsThe classifier achieved 90.9% accuracy (40/44 datasets) in differentiating conditions in leave-one-out cross-validation, and 100% when trained on the full dataset. Simulated effusion and soft-tissue fixation were associated with broadband mobility decreases of 17.5 dB and 8.0 dB, respectively, averaged across both locations. Prosthesis disconnection at the stapes and at the tympanic membrane led to low-frequency (500 and 750 Hz) mobility increases of 9.9 dB and 11.1 dB, respectively, averaged across both locations.
conclusionIn a cadaveric model of post-surgical CHL, OCT vibrometry accurately distinguished effusion, soft-tissue fixation, and prosthesis disconnection. The ability to identify the cause of post-surgical CHL highlights OCT vibrometry's potential to assist clinical decision-making in revision surgery.
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