Evidence map›Paper›PMID 41530603›Full record

ArticleActa neurochirurgica2026

Endoscopic repair of large dural defects in transsphenoidal surgery by suturing acellular dermal matrix graft with the dura: a technical note.

Wei Quan, Sheng-Li Hu, Da-Wei Zhao, Lan Li, Huan-Ran Chen, Long Wang, Hua Feng, Rong Hu

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PubMed Full text at PMC Publisher
In one paragraph

Article in Acta neurochirurgica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Wei Quan *Department of Neurosurgery, Southwest Hospital, Army Medical University (Third Military Medical University), No. 30, Gaotanyan, Shapingba District, Chongqing, 400038, China.
Sheng-Li Hu *Department of Neurosurgery, Southwest Hospital, Army Medical University (Third Military Medical University), No. 30, Gaotanyan, Shapingba District, Chongqing, 400038, China.
Da-Wei Zhao *Department of Neurosurgery, Southwest Hospital, Army Medical University (Third Military Medical University), No. 30, Gaotanyan, Shapingba District, Chongqing, 400038, China.
Lan LiDepartment of Neurosurgery, Southwest Hospital, Army Medical University (Third Military Medical University), No. 30, Gaotanyan, Shapingba District, Chongqing, 400038, China.
Huan-Ran ChenDepartment of Neurosurgery, Southwest Hospital, Army Medical University (Third Military Medical University), No. 30, Gaotanyan, Shapingba District, Chongqing, 400038, China.
Long WangDepartment of Neurosurgery, Southwest Hospital, Army Medical University (Third Military Medical University), No. 30, Gaotanyan, Shapingba District, Chongqing, 400038, China.
Hua FengDepartment of Neurosurgery, Southwest Hospital, Army Medical University (Third Military Medical University), No. 30, Gaotanyan, Shapingba District, Chongqing, 400038, China.
Rong HuDepartment of Neurosurgery, Southwest Hospital, Army Medical University (Third Military Medical University), No. 30, Gaotanyan, Shapingba District, Chongqing, 400038, China. huchrong@tmmu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo introduce acellular dermal matrix (ADM) suturing as a novel repair method for intraoperative high-flow cerebrospinal fluid (CSF) leakage during transsphenoidal surgery (TSA), aiming to replace autologous fat/fascia lata grafts and reduce surgical morbidity.

methodsFive patients (2 invasive pituitary adenomas, 2 craniopharyngiomas, 1 epidermoid cyst) underwent total sellar/suprasellar tumor resection and presented intraoperative high-flow CSF leakage. ADM grafts were tailored to dural defects and sutured directly to native dural edges. Outcomes included repair integrity, operative efficiency, and postoperative complications (CSF leakage, infection).

resultsAll cases achieved dural closure without autologous tissue harvesting. Mean operative time was reduced by avoiding graft harvest procedures. No postoperative CSF leakage or intracranial infections occurred. At 30-day follow-up, all patients exhibited satisfactory recovery with stable skull base reconstruction.

conclusionADM suture repair eliminates donor-site morbidity and shortens operative time while providing robust dural sealing. This technique may be a promising alternative to conventional autologous grafts for high-flow CSF leakage management, warranting larger-scale validation.

Indexed as

Acellular DermisDura MaterEndoscopyNeuroendoscopyNeurosurgical ProceduresPituitary NeoplasmsSuture TechniquesAdenomaAdultCerebrospinal Fluid LeakCraniopharyngiomaEpidermal CystFemaleHumansMaleMiddle AgedAcellular dermal matrixCerebrospinal fluid leakageDural suturingSkull base surgeryTranssphenoidal surgical approach

Identifiers

PMID41530603
PMCPMC12804199

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.