Evidence map›Paper›PMID 41530490›Full record

ArticlePediatric research2026

Apneic time during intubation in critically ill children.

Theerapon Jariyasakoolroj, Taiki Kojima, Shefali Godara, Priyanka Kharayat, Natalie Napolitano, Kathryn Graham, Lindsay Shepard, Vinay Nadkarni, Aaron Donoghue, Akira Nishisaki

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Article in Pediatric research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Theerapon JariyasakoolrojCenter for Simulation, Advanced Education and Innovation, Children's Hospital of Philadelphia, Philadelphia, PA, USA. nui_th2@hotmail.com.
Taiki KojimaDepartment of Anesthesiology, Aichi Children's Health and Medical Center, Obu, Aichi, Japan.
Shefali GodaraDepartment of Pulmonary and Critical Care Medicine, Wayne State University School of Medicine, Detroit, MI, USA.
Priyanka KharayatPediatric Critical Care Medicine, Department of Pediatrics, Phoenix Children's Hospital, Phoenix, AZ, USA.
Natalie NapolitanoRespiratory Therapy Department, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Kathryn GrahamDivision of Critical Care Medicine, Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Lindsay ShepardDivision of Critical Care Medicine, Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Vinay NadkarniCenter for Simulation, Advanced Education and Innovation, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Aaron DonoghueCenter for Simulation, Advanced Education and Innovation, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Akira NishisakiCenter for Simulation, Advanced Education and Innovation, Children's Hospital of Philadelphia, Philadelphia, PA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundProlonged apneic time during tracheal intubation (TI) may increase the risk of oxygen desaturation in critically ill children. This study aimed to identify factors associated with long apneic times and examine the relationship between apneic duration and oxygen desaturation.

methodsWe conducted a prospective observational study of children <18 years undergoing oral TI in the pediatric intensive care unit and emergency department of a large academic children's hospital. Apneic time was measured and categorized as short or long using a 54-s cutoff. Desaturation was defined as SpO₂ <90% during the apneic period in children with baseline SpO₂ >90%.

resultsAmong 204 TIs, the median apneic time was 54 s. Long apneic times were more common in infants than in younger children or older children. Apneic time did not differ by history of a difficult airway, provider type, laryngoscope type, or apneic oxygenation use. Oxygen desaturation rates were similar between long and short groups. There was no significant association between long apneic time and desaturation while apneic oxygenation significantly reduced desaturation risk.

conclusionsPatient age was associated with long apneic times. While apneic time was not associated with desaturation, apneic oxygenation use was associated with lower occurrence of oxygen desaturation. IMPACT: This study found that longer apneic times during pediatric tracheal intubation were not independently associated with oxygen desaturation after adjusting for patient age and apneic oxygenation use. Apneic oxygenation significantly reduced the risk of desaturation, supporting its routine use during tracheal intubation in critically ill children. These findings add evidence supporting age-specific airway strategies and highlight the importance of modifiable practices to improve the safety of pediatric airway management.

Identifiers

PMID41530490

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.