ArticleNature immunology2026
Stability and progressive differentiation of T
Abstract read
In one paragraph
Article in Nature immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- Regulation of follicular helper T cell subset differentiation in health and disease.Journal of molecular medicine (Berlin, Germany) · 2026Review
- CD137 agonists in mice suppress germinal center responses by increasing the immunosuppressive activity of follicular regulatory T-cells.The EMBO journal · 2026Article
- Clonal sharing and plasticity of follicular CD4 + T cells across lymph nodes and tumors in non-small cell lung cancer.Nature communications · 2026Article
- Siglec-G on B cells restrains the germinal center response by controlling T cell help during positive selection.bioRxiv : the preprint server for biology · 2026Article
- Follicular T cells in the ovarian cancer immune microenvironment: biological insights and translational implications.Frontiers in immunology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
20 authors.
Jeong-Mi LeeDepartment of Medicine, Transplantation Research Center, Division of Renal Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Paulo Lisboa RaederDepartment of Medicine, Transplantation Research Center, Division of Renal Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Ridwan B RashidDepartment of Medicine, Transplantation Research Center, Division of Renal Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Hengcheng ZhangDepartment of Medicine, Transplantation Research Center, Division of Renal Medicine, Brigham and Women's Hospital, Boston, MA, USA.ORCID http://orcid.org/0000-0002-2562-1247
Cody S NelsonDepartment of Medicine, Transplantation Research Center, Division of Renal Medicine, Brigham and Women's Hospital, Boston, MA, USA.ORCID http://orcid.org/0000-0002-1046-455X
Sierra G RichardsonDepartment of Medicine, Transplantation Research Center, Division of Renal Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Kelly P BurkeDepartment of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, USA.ORCID http://orcid.org/0000-0003-2187-0147
Pragya ChandrakarDepartment of Medicine, Transplantation Research Center, Division of Renal Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Manuel A PodestàDepartment of Medicine, Transplantation Research Center, Division of Renal Medicine, Brigham and Women's Hospital, Boston, MA, USA.ORCID http://orcid.org/0000-0001-6684-2524
Maya G GemplerDepartment of Medicine, Transplantation Research Center, Division of Renal Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Cole BattyDepartment of Cancer Immunology and Virology, Dana Farber Cancer Institute, Boston, MA, USA.ORCID http://orcid.org/0000-0002-5631-2623
Dejun KongDepartment of Surgery and Center for Vascular and Inflammatory Diseases, University of Maryland School of Medicine, Baltimore, MD, USA.
Samuel J GavzyDepartment of Surgery and Center for Vascular and Inflammatory Diseases, University of Maryland School of Medicine, Baltimore, MD, USA.ORCID http://orcid.org/0000-0002-4880-0301
Marina W ShirkeyDepartment of Surgery and Center for Vascular and Inflammatory Diseases, University of Maryland School of Medicine, Baltimore, MD, USA.
Cyrus YangTaiwanBio Therapeutics, Taipei, Taiwan.
Jonathan S BrombergDepartment of Surgery and Center for Vascular and Inflammatory Diseases, University of Maryland School of Medicine, Baltimore, MD, USA.ORCID http://orcid.org/0000-0002-1407-8795
Marcia C HaigisDepartment of Cell Biology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.ORCID http://orcid.org/0000-0003-2530-2681
Wayne A MarascoDepartment of Cancer Immunology and Virology, Dana Farber Cancer Institute, Boston, MA, USA.ORCID http://orcid.org/0000-0003-3764-4611
Arlene H SharpeDepartment of Immunology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.ORCID http://orcid.org/0000-0002-9736-2109
Peter T SageDepartment of Medicine, Transplantation Research Center, Division of Renal Medicine, Brigham and Women's Hospital, Boston, MA, USA. psage@bwh.harvard.edu.ORCID http://orcid.org/0000-0002-7287-0326
Funding
Physician Scientist Training in Cancer ResearchT32CA009172 · NCI · DANA-FARBER CANCER INSTITUTE · PI Jennifer R Brown, James A. DeCaprio · 1985 to 2026
$17.1MMedical Scientist Training Program Training GrantT32GM145449 · NIGMS · DUKE UNIVERSITY · PI Christopher D Kontos · 2022 to 2026
$6.6MIdentification of Metabolic and Immune Deficits in the Aged Population and Their Restoration to Achieve Youthful Anti-Influenza Vaccine ResponsivenessU01AI165442 · NIAID · DANA-FARBER CANCER INST · PI Wayne A. Marasco · 2022 to 2026
$5.9MHumoral Immunoregulation of Allergic Disease by Follicular T Cell SubsetsR01AI153124 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI Peter The Sage · 2021 to 2026
$3.2MControl of Humoral and Cellular Immunity to Viral Infections of the Lung by Follicular CD8 T CellsR01AI158413 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI SAGE, PETER THE · 2021 to 2025
$2.5MNCI NIH HHS T32 CA009172NIAID NIH HHS R01 AI153124NIAID NIH HHS R01 AI158413NIAID NIH HHS U01 AI165442NIGMS NIH HHS T32 GM145449U.S. Department of Health & Human Services | NIH | National Institute of Allergy and Infectious Diseases (NIAID) R01AI153124U.S. Department of Health & Human Services | NIH | National Institute of Allergy and Infectious Diseases (NIAID) R01AI158413U.S. Department of Health & Human Services | NIH | National Institute of Allergy and Infectious Diseases (NIAID) U01AI165442
Abstract
Follicular regulatory T (T
Indexed as
Cell DifferentiationT Follicular Helper CellsT-Lymphocytes, Helper-InducerT-Lymphocytes, RegulatoryAnimalsB-LymphocytesForkhead Transcription FactorsGerminal CenterHepatocyte Nuclear Factor 1-alphaImmunity, HumoralMiceMice, Inbred C57BLMice, KnockoutPositive Regulatory Domain I-Binding Factor 1Proto-Oncogene Proteins c-bcl-6Bcl6 protein, mouseForkhead Transcription FactorsFoxp3 protein, mouseHepatocyte Nuclear Factor 1-alphaHnf1a protein, mousePositive Regulatory Domain I-Binding Factor 1Prdm1 protein, mouseProto-Oncogene Proteins c-bcl-6
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LicenceCC BY-NC-ND
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.