[Controlled synthesis of high-capacity bisphenol A molecularly imprinted polymer and its application to the detection of environmental water samples].

Bisphenol A （BPA） is an endocrine-disrupting chemical that mimics estrogen， thereby interfering with human hormonal balance and leading to reproductive abnormalities， developmental disorders， and increased risks of obesity， diabetes， and cancer. Commonly found in plastic products and food packaging materials， BPA can readily leach from packaging under thermal stress or exposure to acidic/alkaline conditions， subsequently migrating into the environment. This results in its widespread presence in surface water， groundwater， and drinking water systems. Prolonged exposure poses significant health threats， while conventional wastewater treatment processes prove inadequate for its complete removal. Therefore， developing an efficient， highly specific， and reusable material for removing BPA from water systems is of substantial practical significance. Molecularly imprinted polymers （MIPs） have emerged as promising candidates for targeted pollutant removal due to their artificially created recognition sites that exhibit both structural and functional complementarity to template molecules. The unique advantages of MIPs， including their exceptional specificity， chemical stability， and reusability， make them particularly suitable for environmental applications. To address the challenge of BPA contamination in water systems， we developed a novel cobalt-nickel bimetallic metal-organic framework-based molecularly imprinted polymer （CoNi-MOF-MIPs） through an innovative surface imprinting approach. The fabrication process involved multiple carefully controlled steps. Initially， a crystalline CoNi-MOF substrate was synthesized as the supporting matrix， providing high surface area and structural stability. Dopamine hydrochloride （DA） was then employed as the functional monomer， which underwent self-polymerization under weakly alkaline conditions to form a polydopamine （PDA） coating while simultaneously immobilizing BPA template molecules through synergistic hydrogen bonding and