Evidence map›Paper›PMID 41529888›Full record

ArticleBMJ open2026

Respiratory syncytial virus (RSV) notifications and trends in the transmission cycles from infants and young children to older adults in Ireland: an analysis of incidence shifts over a decade.

Roy K Philip, Kaushik Mangroo, Natalie Gendy, Helen Purtill, Eva Kelly, Lisa Domegan, Maureen O'Leary

Abstract read
In one paragraph

Article in BMJ open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Roy K PhilipNeonatology-Paediatrics, University Maternity Hospital Limerick, Limerick, Ireland roykphilip@gmail.com.ORCID http://orcid.org/0000-0002-6097-9869
Kaushik MangrooNeonatology-Paediatrics, University Maternity Hospital Limerick, Limerick, Ireland.
Natalie GendyNeonatology-Paediatrics, University Maternity Hospital Limerick, Limerick, Ireland.
Helen PurtillMathematics and Statistics, University of Limerick, Limerick, Ireland.
Eva KellyPublic Health, Health Protection Surveillance Centre, Dublin, Ireland.
Lisa DomeganPublic Health, Health Protection Surveillance Centre, Dublin, Ireland.
Maureen O'LearyPublic Health, Health Protection Surveillance Centre, Dublin, Ireland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesUnderstanding the epidemiological shifts of respiratory syncytial virus (RSV) is essential to inform public health interventions, particularly given its increased burden on healthcare systems post-COVID-19 pandemic. This study aimed to examine age-specific trends and seasonal variations in RSV incidence, considering the recent introduction of a newborn RSV immunisation programme in Ireland.

designA surveillance time series study analysing routinely collected RSV notification data. SETTINGS: National-level weekly RSV notifications collected by the Health Service Executive-Health Protection Surveillance Centre in Ireland from 2012 to 2024.

participantsInfants (<1 year), young children (1-4 years) and older adults (≥65 years) with laboratory-confirmed RSV, from within the corresponding Irish population. OUTCOME MEASURES: Annual trends in RSV epidemiology with special reference to the pre- and post-COVID-19 winter surges, and the time lag in age-related transmission to peak incidence among the various age groups. Data were analysed to evaluate incidence rates, peak timing, age-related transmission trends and lag times before and after the COVID-19 pandemic.

resultsThe study examined the increasing incidence of RSV post-COVID-19 and a significant shift toward earlier RSV peaks in recent years (2021/2022, 2022/2023 and 2023/2024 seasons) in Ireland, with the onset and peak of the season nearly 2 months earlier than in pre-COVID-19 pandemic seasons (p<0.01). Cross-correlation factor analysis indicated a sequential spread of RSV infections, where a peak in older adults followed an initial rise in cases among infants and young children, within a 3- to 5-week period (maximum cross-correlation=0.86 at lag 4 weeks, p<0.001). Post-pandemic, infants exhibited higher infection rates, with incident rates significantly higher in all seasons post-COVID-19 (p<0.001) and peak intensities increasing by over 60% from 2021/2022 to 2023/2024.

conclusionThis analysis highlights an early seasonal onset and intensified RSV burden among infants in recent winters (2021/2022, 2022/2023 and 2023/2024 seasons). Quantifying the time lag for the community-level RSV transmission from infants and young children to older adults will offer insights to optimise RSV intervention strategies as a 'life-course approach' to alleviate healthcare system pressures during peak seasons.

Indexed as

COVID-19Respiratory Syncytial Virus InfectionsAdolescentAgedChild, PreschoolFemaleHumansIncidenceInfantInfant, NewbornIrelandMaleRespiratory Syncytial Virus, HumanSARS-CoV-2SeasonsEpidemiologyGERIATRIC MEDICINEimmunisationNEONATOLOGYPaediatric intensive & critical careRSV

Identifiers

PMID41529888
PMCPMC12815040

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.