Evidence map›Paper›PMID 41529264›Full record

ArticleACS nano2026

Separation-Free Extracellular Vesicle Microribonucleic Acid Profiling Using Structurally Oriented Membrane Fusion and Spatially Confined Amplification.

Sihui Tong, Xiaoyi Fu, Lubin Qi, Haixin Wang, Jinglong Tang, Dunqiang Ren, Hongmei Wang, Yuting Bao, Liang Yuan, Chenjing Wang and 9 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS nano, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Sihui TongSchool of Molecular Medicine, Hangzhou lnstitute for Advanced·Study, University of Chinese Academy of Sciences, Hangzhou 310024, PR China.
Xiaoyi FuHangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Zhejiang, Hangzhou 310022, PR China.
Lubin QiHangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Zhejiang, Hangzhou 310022, PR China.ORCID 0000-0002-1665-5816
Haixin WangHangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Zhejiang, Hangzhou 310022, PR China.
Jinglong TangDepartment of Respiratory and Critical Care Medicine, The Affiliated Hospital of Qingdao University, Qingdao 266071, China.ORCID 0000-0001-9981-7966
Dunqiang RenDepartment of Respiratory and Critical Care Medicine, The Affiliated Hospital of Qingdao University, Qingdao 266071, China.
Hongmei WangDepartment of Respiratory and Critical Care Medicine, The Affiliated Hospital of Qingdao University, Qingdao 266071, China.
Yuting BaoHangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Zhejiang, Hangzhou 310022, PR China.
Liang YuanSchool of Molecular Medicine, Hangzhou lnstitute for Advanced·Study, University of Chinese Academy of Sciences, Hangzhou 310024, PR China.
Chenjing WangHangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Zhejiang, Hangzhou 310022, PR China.
Songlin LiuHangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Zhejiang, Hangzhou 310022, PR China.
Yida LiuSchool of Molecular Medicine, Hangzhou lnstitute for Advanced·Study, University of Chinese Academy of Sciences, Hangzhou 310024, PR China.
Peng ZhouSchool of Molecular Medicine, Hangzhou lnstitute for Advanced·Study, University of Chinese Academy of Sciences, Hangzhou 310024, PR China.
Yanglan XuSchool of Molecular Medicine, Hangzhou lnstitute for Advanced·Study, University of Chinese Academy of Sciences, Hangzhou 310024, PR China.
Jinghui RuanHangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Zhejiang, Hangzhou 310022, PR China.
Xun LiSchool of Molecular Medicine, Hangzhou lnstitute for Advanced·Study, University of Chinese Academy of Sciences, Hangzhou 310024, PR China.
Yifei JiangSchool of Molecular Medicine, Hangzhou lnstitute for Advanced·Study, University of Chinese Academy of Sciences, Hangzhou 310024, PR China.ORCID 0000-0003-1818-4541
Yating XiaoSchool of Molecular Medicine, Hangzhou lnstitute for Advanced·Study, University of Chinese Academy of Sciences, Hangzhou 310024, PR China.ORCID 0009-0004-8060-8792
Xiaohong FangSchool of Molecular Medicine, Hangzhou lnstitute for Advanced·Study, University of Chinese Academy of Sciences, Hangzhou 310024, PR China.ORCID 0000-0002-2018-0542

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Current methods for profiling of extracellular vesicle (EV) microRNAs (miRNAs) involve either PCR or sequencing analysis of EV lysate or delivery of RNA probes into EVs for

Indexed as

Aptamers, NucleotideBiosensing TechniquesExtracellular VesiclesMembrane FusionMicroRNAsCarcinoma, Non-Small-Cell LungHumansLiposomesLung NeoplasmsAptamers, NucleotideLiposomesMicroRNAsextracellular vesiclesliquid biopsymembrane fusionmolecular diagnosticsmultiplexed biomarker profiling

Identifiers

PMID41529264
PMCPMC12854732

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.