Observational studyAnesthesiology2026
Severe Postoperative Bleeding after Heart Transplantation.
Observational study in Anesthesiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Risk factors for massive postoperative bleeding after orthotopic heart transplantation: a retrospective cohort study.Journal of cardiothoracic surgery · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPostoperative bleeding is frequent in cardiac surgery, but its incidence, risk factors, and consequences remain largely unknown after heart transplantation. The main objective of this study was to describe the incidence of severe bleeding complications after adult heart transplantation.
methodsThe authors conducted an observational study including all adult patients who received a heart transplant between 2015 and 2022 in two French referral centers. The primary endpoint was the incidence of severe bleeding complications defined by a Universal Definition of Perioperative Bleeding score of 3 or greater. Multivariable logistic regression was used to identify variables associated with the incidence of severe postoperative bleeding. The impact of severe postoperative bleeding on 1-yr mortality was evaluated using a multivariable Cox regression model.
resultsAmong the 446 patients included, 112 (25%) developed severe bleeding. In multivariable analysis, long-term mechanical cardiac support (adjusted odds ratio [adjOR; 95% CI], 2.21 [1.01 to 4.88]), preoperative hemoglobin (adjOR, 0.85 [0.76 to 0.95]) and the duration of cardiopulmonary bypass (per 10-min increase; adjOR, 1.08 [1.03 to 1.15]) were associated with severe bleeding. Severe postoperative bleeding was associated with an increased mortality at 1 yr (35% vs. 13%; P < 0.001), with an adjusted hazard ratio of 1.91 (95% CI, 1.18 to 3.09; P = 0.008).
conclusionsThis study reports a high incidence of severe hemorrhagic complications after heart transplantation, particularly in patients with mechanical circulatory support. Bleeding complications were associated with a significant increase in morbidity and mortality. Larger-scale studies are needed to identify and evaluate potential prevention strategies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.