Evidence map›Paper›PMID 41529027›Full record

ArticlePloS one2026

Colorectal cancer incidence, survival analysis and predictions (Monastir, Tunisia: 2002-2030).

Cyrine Bennasrallah, Amani Maatouk, Mariem Kacem, Wafa Dhouib, Hela Abroug, Manel Ben Fredj, Leila Safer, Sonia Zaied, Moncef Mokni, Ines Bouanène and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Cyrine BennasrallahDepartment of Epidemiology and Preventive Medicine, Faculty of Medicine of Monastir, University Hospital Fattouma Bourguiba of Monastir, University of Monastir, Monastir, Tunisia.
Amani MaatoukDepartment of Epidemiology and Preventive Medicine, Faculty of Medicine of Monastir, University Hospital Fattouma Bourguiba of Monastir, University of Monastir, Monastir, Tunisia.
Mariem KacemDepartment of Epidemiology and Preventive Medicine, Faculty of Medicine of Monastir, University Hospital Fattouma Bourguiba of Monastir, University of Monastir, Monastir, Tunisia.
Wafa DhouibDepartment of Epidemiology and Preventive Medicine, Faculty of Medicine of Monastir, University Hospital Fattouma Bourguiba of Monastir, University of Monastir, Monastir, Tunisia.
Hela AbrougFaculty of Medicine of Monastir, Technology and Medical Imaging Research Laboratory - LTIM - LR12ES06, University of Monastir, Monastir, Tunisia.
Manel Ben FredjFaculty of Medicine of Monastir, Technology and Medical Imaging Research Laboratory - LTIM - LR12ES06, University of Monastir, Monastir, Tunisia.
Leila SaferDepartment of Gastroenterology, Faculty of Medicine of Monastir, University Hospital Fattouma Bourguiba of Monastir, Monastir, Tunisia.
Sonia ZaiedDepartment of Oncology, Faculty of Medicine of Monastir, University Hospital Fattouma Bourguiba of Monastir, Monastir, Tunisia.
Moncef MokniCancer Registry of the Center of Tunisia, University Hospital Farhat Hached of Sousse, Sousse, Tunisia.
Ines BouanèneDepartment of Epidemiology and Preventive Medicine, Faculty of Medicine of Monastir, University Hospital Fattouma Bourguiba of Monastir, University of Monastir, Monastir, Tunisia.
Asma Belguith SrihaDepartment of Epidemiology and Preventive Medicine, Faculty of Medicine of Monastir, University Hospital Fattouma Bourguiba of Monastir, University of Monastir, Monastir, Tunisia.ORCID https://orcid.org/0000-0001-5167-5102
Imen ZemniDepartment of Epidemiology and Preventive Medicine, Faculty of Medicine of Monastir, University Hospital Fattouma Bourguiba of Monastir, University of Monastir, Monastir, Tunisia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundColorectal cancer (CRC) ranks as the third most common cancer and the second leading cause of cancer death in Tunisia. The aim of this study was to describe the incidence and mortality rates, to determine CRC trends, prediction and burden and to analyses the CRC survival outcomes.

methodsWe conducted population-based cohort study.of all CRC cases diagnosed between 2002 and 2014 in the governorate of Monastir, with follow-up until 2022. Data were obtained from the Central Cancer Registry, the Hospital Morbidity and Mortality Registry, and national mortality databases, ensuring comprehensive case identification. Incidence, mortality, disability-adjusted life years (DALYs), Annual Percentage Change (APC), and survival were analyzed using standardized methods.

resultsWe identified 876 cases of CRC. The age-standardized incidence rate (ASIR) was 13.5/100,000 PY (95% CI: 9.8-17.2), with a significant upward trend (APC = +6.09% (95% CI: + 0.64; + 11.82).). The predicted ASIR for 2030 was 60.4 per 100,000 PY (95% CI: 52.0-68.2). The rectum being the most frequent site (32.9%), followed by the recto-sigmoid region (28.3%). The age-standardized mortality rate was 9.6/100,000 PY (95% CI: 6.5-12.7). The DALY/year/ 100,000 PY was 96.0 (86.2-105.8). Survival rate was 64% (95% CI: 62.3-66.2), at one year and 21.1% (95% CI: 19.3-22.9) at five years.

conclusionCRC incidence and mortality in Monastir have increased significantly, with projections indicating a continued rise by 2030. Strengthening population-based screening and early detection could help reverse these trends and improve prognosis.

Indexed as

Colorectal NeoplasmsAdultAgedAged, 80 and overDisability-Adjusted Life YearsFemaleHumansIncidenceMaleMiddle AgedRegistriesSurvival AnalysisTunisia

Identifiers

PMID41529027
PMCPMC12798969

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.