ArticleJournal of chemical information and modeling2026
The Blobulator: A Toolkit for Identification and Visual Exploration of Hydrophobic Modularity in Protein Sequences.
Connor Pitman, Ezry Santiago-McRae, Ruchi Lohia, Ryan Lamb, Kaitlin Bassi, Lindsey Riggs, Thomas T Joseph, Matthew E B Hansen, Grace Brannigan
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In one paragraphArticle in Journal of chemical information and modeling, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
9 authors.
Connor PitmanCenter for Computational and Integrative Biology, Rutgers University-Camden, 201 Broadway, Camden, New Jersey 08103, United States.ORCID 0009-0008-5594-9906 Ezry Santiago-McRaeCenter for Computational and Integrative Biology, Rutgers University-Camden, 201 Broadway, Camden, New Jersey 08103, United States.ORCID 0000-0002-0930-8277 Ruchi LohiaDepartment of Cancer Biology, Perelman School of Medicine, University of Pennsylvania, 3400 Civic Center Blvd, Philadelphia, Pennsylvania 19104, United States.
Ryan LambCenter for Computational and Integrative Biology, Rutgers University-Camden, 201 Broadway, Camden, New Jersey 08103, United States.
Kaitlin BassiCenter for Computational and Integrative Biology, Rutgers University-Camden, 201 Broadway, Camden, New Jersey 08103, United States.
Lindsey RiggsCenter for Computational and Integrative Biology, Rutgers University-Camden, 201 Broadway, Camden, New Jersey 08103, United States.
Thomas T JosephDepartment of Anesthesiology and Critical Care, Perelman School of Medicine, University of Pennsylvania, JMB 305, 3620 Hamilton Walk, Philadelphia, Pennsylvania 19104, United States.ORCID 0000-0003-1323-3244 Matthew E B HansenDepartment of Genetics, Perelman School of Medicine, University of Pennsylvania, 3400 Civic Center Blvd, Philadelphia, Pennsylvania 19104, United States.
Grace BranniganCenter for Computational and Integrative Biology, Rutgers University-Camden, 201 Broadway, Camden, New Jersey 08103, United States.ORCID 0000-0001-8949-2694 Funding
Integrative Genomic Analyses of Human Evolution and Adaptation in AfricaR35GM134957 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI TISHKOFF, SARAH ANNE · 2020 to 2024
$2.7MEfficient prediction of transmembrane binding sites for anesthetic ligandsK08GM139031 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI JOSEPH, THOMAS THENGANPALLIL · 2020 to 2024
$984kNIGMS NIH HHS K08 GM139031NIGMS NIH HHS R35 GM134957
6 · The paper itselfAbstract
While contiguous subsequences of hydrophobic residues are essential to protein structure and function, as in the hydrophobic core and transmembrane regions, there are no current bioinformatics tools for module identification focused on hydrophobicity. To fill this gap, we created the
Indexed as
Computational BiologyProteinsSoftwareAlgorithmsAmino Acid SequenceHumansHydrophobic and Hydrophilic InteractionsMolecular Dynamics SimulationProteins
Identifiers
PMID41528931
PMCPMC12848970
What OpenQuestion holds
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