ReviewWorld journal of microbiology & biotechnology2026
Recent advances in metabolic engineering for microbial production of L-tyrosine.
Review in World journal of microbiology & biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Development of Bacillus subtilis cell factories for nutraceuticals production.World journal of microbiology & biotechnology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
L-Tyrosine, an important aromatic amino acid, has broad applications in food, feed, pharmaceuticals, nutraceuticals, and materials industries, with consistently growing market demand. Conventional production methods face drawbacks such as low efficiency and significant environmental impact. In contrast, microbial cell factories offer a promising alternative due to their environmental friendliness, sustainability, and controllability. This review systematically summarizes recent advances in metabolic engineering strategies for L-tyrosine production, including key enzyme overexpression and engineering, pathway optimization, and enhancement of precursor, cofactor, and transport systems. It also explores prospective research directions to address ongoing challenges such as complex metabolic networks and product inhibition, including systems biology-guided global optimization, dynamic regulation, and diversified substrate utilization. Overall, this review aims to provide a theoretical and technical foundation for advancing efficient, economical, and sustainable L-tyrosine biomanufacturing.
Indexed as
Identifiers
41528593What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.