Evidence map›Paper›PMID 41528555›Full record

Observational studySupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2026

Exploring the unseen consequences: effects of cancer treatment on pelvic health and quality of life in breast cancer survivors-a matched cross-sectional observational study.

Ana Lozano-Rubio, Cristina Salar-Andreu, Sergio Montero-Navarro, Marie Riquier, Francisco J Molina-Payá, María Torres-Lacomba, Josep C Benítez-Martínez, Jesús Sánchez-Más, Cristina Orts-Ruiz

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ana Lozano-Rubio *Physical Therapy Department, Health Sciences Faculty, CEU-Cardenal Herrera University, CEU Universities, Plaza Reyes Católicos, 19, 03204, Elche, Spain.
Cristina Salar-Andreu *Physical Therapy Department, Health Sciences Faculty, CEU-Cardenal Herrera University, CEU Universities, Plaza Reyes Católicos, 19, 03204, Elche, Spain.
Sergio Montero-NavarroPhysical Therapy Department, Health Sciences Faculty, CEU-Cardenal Herrera University, CEU Universities, Plaza Reyes Católicos, 19, 03204, Elche, Spain.
Marie RiquierPhysical Therapy Department, Health Sciences Faculty, CEU-Cardenal Herrera University, CEU Universities, Plaza Reyes Católicos, 19, 03204, Elche, Spain.
Francisco J Molina-PayáPhysical Therapy Department, Health Sciences Faculty, CEU-Cardenal Herrera University, CEU Universities, Plaza Reyes Católicos, 19, 03204, Elche, Spain.
María Torres-LacombaFaculty of Medicine and Health Sciences, Physiotherapy and Nursing Department, University of Alcalá, Madrid, Spain.
Josep C Benítez-MartínezResearch Group On Physiotherapy Technology and Recovering (FTR), University of Valencia, Av. de Blasco Ibáñez, 13, 46010, Valencia, Spain.
Jesús Sánchez-MásBiomedical Sciences Department, Health Sciences Faculty, CEU-Cardenal Herrera University, CEU Universities, Plaza Reyes Católicos 19, 03204, Elche, Spain. jesus.sanchez@uchceu.es.ORCID http://orcid.org/0000-0002-7739-2976
Cristina Orts-RuizPhysical Therapy Department, Health Sciences Faculty, CEU-Cardenal Herrera University, CEU Universities, Plaza Reyes Católicos, 19, 03204, Elche, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeBreast cancer treatments cause hormonal and sexual alterations that can leave physical and psychological sequelae. The purpose of this study is to establish the incidence of pelvic floor dysfunction (PFD) in female breast cancer survivors and its relationship with the cancer treatment received, as well as the impact on quality of life.

methodsWe conducted a matched cross-sectional observational study involving 150 female breast cancer survivors from Alicante (Spain) and 287 age-matched women as a control group. Demographic, anthropometric, obstetric, and lifestyle habits data were collected for all participants, and data related to breast cancer were additionally collected for breast cancer survivors. The Pelvic Floor Distress Inventory (PFDI-20) and the Pelvic Floor Impact Questionnaire (PFIQ-7) were included.

resultsA greater number of breast cancer survivors had menopause compared to the control group. When selecting only participants with menopause, cancer survivors were younger than the control group females with menopause. A higher prevalence of urinary incontinence, pelvic organ prolapse, and flatus incontinence was observed in cancer survivors. Breast cancer survivors presented more PFD symptoms and a greater negative impact on quality of life. Treatment with chemotherapy, radiotherapy, and hormone therapy had a greater negative impact on pelvic function.

conclusionsThe early onset of menopause among breast cancer survivors has a negative impact on pelvic function and quality of life. The association of this symptomatology with the type of cancer treatment received suggests the need to assess and monitor pelvic function from the time of cancer diagnosis and treatment.

Indexed as

Breast NeoplasmsCancer SurvivorsPelvic Floor DisordersQuality of LifeAdultAgedAge FactorsCase-Control StudiesCross-Sectional StudiesFemaleHumansMenopauseMiddle AgedSpainSurveys and QuestionnairesUrinary IncontinenceBreast cancerPelvic functionQuality of lifeTreatment

Identifiers

PMID41528555

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.