ArticleArchives of gynecology and obstetrics2026
The upper airway parameter: the potential prognostic clue for congenital diaphragmatic hernia-a prospective randomized controlled study.
Article in Archives of gynecology and obstetrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
purposeIn our previous studies, differences in the upper airway inner diameter between fetuses with thoracic space occupying lesions and normal fetuses were found, but their clinical value has not been further validated. We designed a prospective case-control animal experiment to validate its prognostic value in congenital diaphragmatic hernia (CDH).
methodsUsing Nitrofen to create a fetal SD-rat model of CDH. Calculate the upper airway inner diameter and lung parameters of fetal rats on ultrasonic image and histology sections, and calculate the correlation between the upper airway and lung parameters. Design experiments to rule out the impact of major cardiac malformations on airway development, the correlation between the upper airway inner diameter and the area of CDH was also calculated.
resultsThere was no significant difference in lung and upper airway parameters between the control group and the group with unsuccessful CDH modeling. The upper airway and lung parameters of fetal rat with CDH were significantly smaller than those without CDH (p < 0.01). The correlation between upper airway inner diameter and lung volume is better than that with lung weight, especially the upper airway inner diameter measured on ultrasound images (p < 0.01, R = 0.76). In the CDH group, the airway lumen diameter was inversely correlated with the hernia area (p = 0.005, R = 0.507).
conclusionsThe upper airway inner diameter of fetal rat was correlated with lung volume, demonstrating the potential predictive value for fetal prognosis of congenital diaphragmatic hernia.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.