Evidence map›Paper›PMID 41528379›Full record

ReviewApplied biochemistry and biotechnology2026

Comprehensive Research Progress on Glucosamine: A Review.

Zihao Zhang, Yunxing Liao, Lele Zhao, Xueting Deng, Zhengbing Guan

Abstract readReview
PubMed Publisher
In one paragraph

Review in Applied biochemistry and biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Glucosamine Yield Improvement in EngineeredFoods (Basel, Switzerland) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zihao ZhangThe Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, 1800 Lihu Road, Wuxi, Jiangsu, 214122, PR China.
Yunxing LiaoThe Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, 1800 Lihu Road, Wuxi, Jiangsu, 214122, PR China.
Lele ZhaoThe Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, 1800 Lihu Road, Wuxi, Jiangsu, 214122, PR China.
Xueting DengThe Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, 1800 Lihu Road, Wuxi, Jiangsu, 214122, PR China.
Zhengbing GuanThe Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, 1800 Lihu Road, Wuxi, Jiangsu, 214122, PR China. guanzb@jiangnan.edu.cn.ORCID http://orcid.org/0000-0002-9644-3548

Funding

National Natural Science Foundation of China 31472003Priority Academic Program Development of Jiangsu Higher Education Institutions No.111-2-06State Key Laboratory of Biocatalysis and Enzyme Engineering SKLBEE2023007
6 · The paper itself

Abstract

As one of the important derivatives of D-glucose, Glucosamine (GlcN) is an amino monosaccharide with various biological activities. GlcN has functions such as enhancing immunity, antioxidation, and antibacterial effects, and it is particularly well known for its role in the treatment of osteoarthritis. This also gives GlcN broad application prospects in the fields of healthcare, food production, and cosmetics, with its global market size projected to exceed 10 billion USD by 2028. As demand grows, its efficient industrial production has been attracting increasing attention. Here, we systematically introduce the functions, raw material sources, metabolic pathways, detection methods, and applications of GlcN in various countries. Particularly, we delve into the strategies for high-yield biosynthesis of GlcN/GlcNAc using metabolically engineered microorganisms, with the highest reported titer reaching 179.7 g/L. This comprehensive overview aims to help readers gain a better understanding of GlcN and explore its potential commercial value and product applications.

Indexed as

GlucosamineHumansMetabolic EngineeringGlucosamineApplications in various countriesDetection methodsFunctionsGlucosamineMetabolism pathwaysRaw material sources

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.