ArticleEuropean journal of trauma and emergency surgery : official publication of the European Trauma Society2026
Application and observation of hemostatic effect of independently developed hemostatic equipment in a lethal swine exsanguination model.
Article in European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectiveSevere hemorrhage is one of the predominant causes of death among trauma patients. Conventional techniques often prove insufficient for hemostasis in junctional injuries. Therefore, this study independently developed a disposable sterile hemostatic clamp. Swine groin models were utilized to evaluate its efficacy.
methods10 healthy Bama Xiang boars aged 6–7 months were divided to two groups. After femoral artery incision, the control group were treated with bandages and the experimental group were treated with hemostatic clamps. The survival rate, survival time, hemostatic operation time, and blood loss were recorded. Local joints were repeatedly flexed to assess the stability of the hemostatic clamp. Physiological parameters were monitored and recorded. Ultrasound was used to observe blood flow perfusion. Local skin was examined and femoral arteries were taken for pathological staining.
resultsIn experimental group and control group, all 5 (100%) and 3 (60%) animals survived, respectively. The survival time of experimental group was all > 180 min, the median survival time and interquartile range of control group were 180 min and 68 min. The hemostatic procedures time were 22.50 ± 2.89 min and 57.25 ± 13.60 min, and blood loss were 190 ± 100 g and 549 ± 195 g, respectively. Ultrasound showed the clamp effectively reduced distal arterial blood flow. It was well-fixed after joint movement, while bandages were loose. No skin damage was observed. Femoral arteries in experimental group showed intravascular thrombosis, while no thrombosis was oberserved in control.
conclusionCompared to traditional bandaging, the hemostatic clamp may help to reduce blood loss and stabilize vital signs, demonstrating its potential in controlling severe pre-hospital hemorrhage.
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