ArticleACS biomaterials science & engineering2026
Residuals of Chemical Cleaning Agents Impair Peri-Implant Cell Viability: An in Vitro Study.
Article in ACS biomaterials science & engineering, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundChemical debridement agents are commonly used during the cleaning of implants for peri-implantitis treatment; however, how these agents affect lesion healing remains unclear. In addition, the dose- and time-dependent effects of these residuals on implant biocompatibility remain poorly understood. MATERIALS AND
methodsWe evaluated the effects of active compounds in commercial products-3% hydrogen peroxide (H
resultsAt high concentrations, H
conclusionResidual chemical debridement agents, when inadequately removed, compromise the viability of cells in peri-implant tissues in a dose- and time-dependent manner. hBMSCs exhibited greater resistance to apoptosis than MC3T3-E1 cells and HGFs. Thorough removal of residual chemical cleaning agents after peri-implant debridement is therefore crucial to preserve the biocompatibility of the implant and the healing potential of peri-implant tissues.
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