Evidence map›Paper›PMID 41527642›Full record

ArticleCureus2025

Integrating Classical Tumor Markers and Systemic Inflammatory Indices for Enhanced Biological Profiling in Testicular Neoplasms.

Sadik Portakal, Basri Cakiroglu, Mustafa Solak

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sadik PortakalDepartment of Family Medicine, Hisar Intercontinental Hospital, Istanbul, TUR.
Basri CakirogluDepartment of Urology, Uskudar University, Istanbul, TUR.
Mustafa SolakDepartment of Oncology, Hisar Intercontinental Hospital, Istanbul, TUR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective This study aimed to explore the diagnostic and prognostic significance of integrating classical tumor markers, including alpha-fetoprotein (AFP), beta-human chorionic gonadotropin (β-HCG), and lactate dehydrogenase (LDH), with inflammatory hematological indices, including neutrophil-to-lymphocyte ratio (NLR) and mean platelet volume-to-platelet ratio (MPV/PLT), in patients with testicular neoplasms. Materials and methods This retrospective study included 85 patients with histologically confirmed testicular tumors (48 seminomas and 37 nonseminomas). Preoperative serum AFP, β-HCG, and LDH levels were analyzed along with the complete blood count parameters. The derived inflammatory indices (NLR and MPV/PLT) were calculated. Intergroup comparisons were performed using the Student's

Indexed as

mpv/pltnlrnon seminomprognostic biomarkerstesticular cancertesticular seminomaβ-hcg

Identifiers

PMID41527642
PMCPMC12790754

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.