Evidence map›Paper›PMID 41527597›Full record

ArticleCureus2025

Unmasking a Silent Persistent Hyaloid Artery: A Rare Cause of Vitreous Hemorrhage in an Elderly Patient.

Eirini Maliagkani, Aikaterini Chatzara, Konstantina Chronopoulou, Ioannis Tservakis

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Eirini Maliagkani1st Department of Ophthalmology, National and Kapodistrian University of Athens Medical School, General Hospital of Athens "G. Gennimatas", Athens, GRC.
Aikaterini Chatzara1st Department of Ophthalmology, National and Kapodistrian University of Athens Medical School, General Hospital of Athens "G. Gennimatas", Athens, GRC.
Konstantina ChronopoulouOphthalmology Department, Eye Day Clinic, Athens, GRC.
Ioannis TservakisOphthalmology Department, Eye Day Clinic, Athens, GRC.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Persistent hyaloid artery (PHA) rupture is a rare cause of vitreous hemorrhage, particularly in older adults, as hyaloid remnants typically regress during early life. We report the case of a 70-year-old man who presented with sudden, painless vision loss in the left eye due to dense vitreous hemorrhage. Immediate pars plana vitrectomy was performed, during which an actively bleeding PHA was identified and successfully cauterized. Intraoperative video documentation provided direct visualization of the ruptured embryonic vessel, confirming the diagnosis. No retinal tears, retinal detachment, or neovascularization were noted. Postoperatively, the patient experienced progressive visual recovery, ultimately returning to his baseline visual acuity. This case expands the known age spectrum of symptomatic PHA, demonstrates the diagnostic and therapeutic value of early vitrectomy in non-clearing hemorrhage, and underscores the importance of considering congenital vascular remnants in the differential diagnosis of spontaneous vitreous hemorrhage in elderly patients.

Indexed as

intraoperative videopars plana vitrectomypersistent fetal vasculaturepersistent hyaloid arteryvitreous hemorrhage

Identifiers

PMID41527597
PMCPMC12790490

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.