Evidence map›Paper›PMID 41527488›Full record

ArticleJournal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.]2026

Peri-Implant Inflammation Varies With Different Restorative Emergence Angles: An Histological Evaluation.

Franz J Strauss, Alberto Monje, Jin-Young Park, Jung-Seok Lee, Sonja Hitz, Ronald E Jung, Jae-Kook Cha, Daniel S Thoma

Abstract read
In one paragraph

Article in Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.], 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Influence of Concave Versus Convex Emergence Profiles on Midfacial Mucosal Stability-A Systematic Review With Meta-Analysis.Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.] · 2026
    Pooled it
  2. Trial
  3. Article
  4. Peri-Implant Supracrestal Resiliency (PSR): A Geometric Determinant Guiding Emergence Profile Execution.Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.] · 2026
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Franz J StraussClinic of Reconstructive Dentistry, Center of Dental Medicine, University of Zurich, Zurich, Switzerland.ORCID https://orcid.org/0000-0002-5832-7327
Alberto MonjeDepartment of Periodontology and Oral Medicine, University of Michigan, Ann Arbor, Michigan, USA.ORCID https://orcid.org/0000-0001-8292-1927
Jin-Young ParkDepartment of Periodontology, Research Institute for Periodontal Regeneration, Yonsei University College of Dentistry, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0002-6408-1618
Jung-Seok LeeDepartment of Periodontology, Research Institute for Periodontal Regeneration, Yonsei University College of Dentistry, Seoul, Republic of Korea.
Sonja HitzClinic of Reconstructive Dentistry, Center of Dental Medicine, University of Zurich, Zurich, Switzerland.
Ronald E JungClinic of Reconstructive Dentistry, Center of Dental Medicine, University of Zurich, Zurich, Switzerland.ORCID https://orcid.org/0000-0003-2055-1320
Jae-Kook ChaDepartment of Periodontology, Research Institute for Periodontal Regeneration, Yonsei University College of Dentistry, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0002-6906-7209
Daniel S ThomaClinic of Reconstructive Dentistry, Center of Dental Medicine, University of Zurich, Zurich, Switzerland.ORCID https://orcid.org/0000-0002-1764-7447

Funding

National Research Foundation of Korea RS-2025-00522998Oral Reconstruction Foundation 32201
6 · The paper itself

Abstract

objectivesTo histologically evaluate peri-implant inflammatory responses associated with varying restorative emergence angles and to assess differences between buccal and lingual implant sites. MATERIALS AND

methodsSix healthy male mongrel dogs received four bone-level implants (3.8 × 7 mm) per hemi-mandible in the posterior mandible. Customized abutments with standardized restorative angles of 20°, 40°, 60°, and 80° were immediately connected. After 24 weeks, all implants were retrieved for histological processing and quantitative analysis of inflammatory cell infiltration within three defined peri-implant soft tissue regions. A linear mixed-effects model was used to compare the groups to account for within-subject correlations.

resultsHistological sections were obtained for all specimens (N = 48). Inflammatory cell counts increased progressively with wider restorative angles, demonstrating a significant dose-dependent relationship (p < 0.001). At buccal sites, inflammation remained low up to 40° (20° = 3%; 40° = 6%) but increased sharply at 60° (≈10%) and 80° (≈13%) (p < 0.001), indicating a threshold beyond which wider emergence angles markedly intensified the inflammatory response. Lingual sites exhibited a similar, though less pronounced pattern. Values were stable up to 40° (20° = 4%; 40° = 3.1%), followed by a moderate rise at 60° (≈7%) and a pronounced increase at 80° (≈12%) (p < 0.001). When both aspects were analyzed together, significant angle-by-site interactions emerged at 40° and 60°, indicating a consistently higher inflammatory response on the buccal compared with the lingual side.

conclusionsWider restorative emergence angles (> 40°) are associated with increased peri-implant inflammatory cell infiltration, particularly at buccal sites. CLINICAL RELEVANCE: Wide restorative emergence angles (> 40°) favor peri-implant inflammation, potentially compromising the long-term stability of peri-implant tissues.

Indexed as

Dental ImplantsPeri-ImplantitisAnimalsDogsMaleMandibleDental Implantsdental implantemergence profileinflammationprosthodonticsti‐basetitanium base

Identifiers

PMID41527488
PMCPMC13069363

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.