ArticleClinical transplantation and research2026
Incidence and risk factors of cytomegalovirus infection in solid organ transplant recipients: a nationwide Korean study.
Article in Clinical transplantation and research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Cytomegalovirus (CMV) remains one of the most important opportunistic infections following solid organ transplantation, with variable incidence and clinical outcomes depending on organ type, immunosuppressive regimen, and donor-recipient serostatus. Methods: We conducted a large-scale retrospective analysis using data from the Korean Organ Transplantation Registry (KOTRY), a prospective multicenter cohort including kidney, liver, heart, and lung transplant recipients. A total of 9,777 adult patients who underwent transplantation between 2014 (lung added in 2015) and December 2022 were analyzed. CMV infection and disease were identified based on clinical diagnosis. Independent risk factors were determined using multivariable Cox regression. Results: The overall incidence of CMV infection was highest among kidney transplant recipients (36.5%), followed by lung (21.3%), liver (12.9%), and heart (6.8%) recipients. Most CMV infections occurred within the first year after transplantation, with lung recipients exhibiting the longest median time to infection (112 days). Risk factors varied by organ: in kidney recipients, antithymocyte globulin (ATG) use and D+/R- serostatus were the strongest predictors; in liver recipients, higher model for end-stage liver disease scores, refractory ascites, and deceased donor status increased the risk; in heart recipients, ATG administration, desensitization, and CMV immunoglobulin G seronegativity were significant risk factors; and in lung recipients, diabetes and prolonged operation time were associated with higher infection rates. CMV infection significantly worsened patient survival among kidney, liver, and lung recipients. Conclusions: The incidence and risk factors of CMV infection differ substantially across organ types, yet its impact on outcomes remains considerable. These findings highlight the need for organ-specific prevention, monitoring, and novel therapeutic strategies to enable personalized management of transplant recipients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.