Evidence map›Paper›PMID 41527386›Full record

ArticleTurk gogus kalp damar cerrahisi dergisi2026

Evolving diagnostic and therapeutic methods in corrosive esophagitis: Evaluation of a diagnostic and therapeutic algorithm based on 26 years of experience.

Mehmet Gökhan Pirzirenli, Caner İşevi, Yunus Köksal, Melda İşevi, Ayşen Taslak Şengül, Burçin Çelik, Selçuk Gürz, Yasemin Büyükkarabacak

Abstract read
In one paragraph

Article in Turk gogus kalp damar cerrahisi dergisi, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mehmet Gökhan PirzirenliDepartment of Thoracic Surgery, Ondokuz Mayıs University Faculty of Medicine, Samsun, Türkiye.ORCID 0000-0002-1831-2710
Caner İşeviDepartment of Thoracic Surgery, Ondokuz Mayıs University Faculty of Medicine, Samsun, Türkiye.ORCID 0000-0002-7496-8220
Yunus KöksalDepartment of Thoracic Surgery, Ondokuz Mayıs University Faculty of Medicine, Samsun, Türkiye.ORCID 0009-0001-7872-6069
Melda İşeviDivision of Intensive Care, Department of Anesthesiology, Ondokuz Mayıs University Faculty of Medicine, Samsun, Türkiye.ORCID 0000-0001-5308-7662
Ayşen Taslak ŞengülDepartment of Thoracic Surgery, Ondokuz Mayıs University Faculty of Medicine, Samsun, Türkiye.ORCID 0000-0002-1558-8228
Burçin ÇelikDepartment of Thoracic Surgery, Ondokuz Mayıs University Faculty of Medicine, Samsun, Türkiye.ORCID 0000-0001-7620-4497
Selçuk GürzDepartment of Thoracic Surgery, Ondokuz Mayıs University Faculty of Medicine, Samsun, Türkiye.ORCID 0000-0003-4584-4840
Yasemin BüyükkarabacakDepartment of Thoracic Surgery, Ondokuz Mayıs University Faculty of Medicine, Samsun, Türkiye.ORCID 0000-0001-9676-9313

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Corrosive esophagitis caused by ingestion of acidic or alkaline substances remains a serious public health issue, especially in developing countries. Despite numerous studies, there is currently no universally accepted treatment algorithm for corrosive esophagitis. This study aims to present a diagnostic and treatment algorithm developed from 26 years of clinical experience and to evaluate current management approaches. Methods: In this retrospective study, patients diagnosed with corrosive esophagitis and admitted to a tertiary thoracic surgery clinic between January 1998 and December 2024 were analyzed. Demographic data, ingested substance type and intent (accidental or suicidal), clinical presentation, diagnostic methods, treatment strategies, and outcomes were evaluated. Endoscopic injury severity was classified using the Zargar system. As this was a descriptive study, no statistical testing was performed. Results: A total of 501 patients were included. Commonly ingested substances were bleach, limescale removers, and detergents. Rigid esophagoscopy was performed in 248 patients (49.5%) and classified using Zargar grades. Oral intake was initiated based on symptoms and injury severity, with a mean of 4.5±5.23 days. All patients received intravenous proton pump inhibitors and antibiotics; corticosteroids were selectively used. Surgery was required in 3 patients due to complications such as perforation and fibrosis, and 8 underwent dilatation for strictures. Four patients (0.8%) died due to airway injury, suicide, or cardiopulmonary arrest. Conclusion: Corrosive esophagitis remains a diagnostic and therapeutic challenge. A symptom- and imaging-based triage approach may guide safe management. Routine corticosteroid use appears unnecessary. The proposed algorithm, based on 26 years of clinical experience, may serve as a practical tool to streamline management and improve patient outcomes.

Indexed as

clinical algorithmCorrosive esophagitisendoscopyesophageal strictureZargar classification

Identifiers

PMID41527386
PMCPMC12794427

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.