Evidence map›Paper›PMID 41527207›Full record

ArticleCatheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions2026

Left Ventricular Outflow Tract Geometry as a Predictor of Permanent Pacemaker Implantation After Transcatheter Aortic Valve Implantation Using the Evolut Series.

Mahmoud Abdelshafy, Angela McInerney, Ahmed Elmeanawy, Paolo Alberto Del Sole, Max Wagener, Hatem Helal, Mahmoud Abozaid, Ashraf Alamir, Tamer Fouad, Alsayed Almarghany and 4 more

Abstract readMulticenter Study
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In one paragraph

Article in Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

14 authors.

Mahmoud AbdelshafyDepartment of Cardiology, Al-Azhar University, Cairo, Egypt.ORCID 0000-0003-1040-0019
Angela McInerneyDepartment of Cardiology, Galway University Hospitals and University of Galway, Galway, Ireland.
Ahmed ElmeanawyDepartment of Cardiology, Nasr City Health Insurance Hospital, Cairo, Egypt.
Paolo Alberto Del SoleDepartment of Cardiology, Galway University Hospitals and University of Galway, Galway, Ireland.ORCID 0000-0002-3638-200X
Max WagenerDepartment of Cardiology, Galway University Hospitals and University of Galway, Galway, Ireland.
Hatem HelalDepartment of Cardiology, Nasr City Health Insurance Hospital, Cairo, Egypt.
Mahmoud AbozaidDepartment of Cardiology, Nasr City Health Insurance Hospital, Cairo, Egypt.
Ashraf AlamirDepartment of Cardiology, Al-Azhar University, Cairo, Egypt.
Tamer FouadDepartment of Cardiology, Al-Azhar University, Cairo, Egypt.
Alsayed AlmarghanyDepartment of Cardiology, Al-Azhar University, Cairo, Egypt.
Briain MacNeillDepartment of Cardiology, Galway University Hospitals and University of Galway, Galway, Ireland.
Osama SolimanRoyal College of Surgeons in Ireland (RCSI), University of Medicine and Health Sciences, Dublin, Ireland.ORCID 0000-0003-0758-3539
Darren MylotteDepartment of Cardiology, Galway University Hospitals and University of Galway, Galway, Ireland.
Mohammad AbdelghaniDepartment of Cardiology, Al-Azhar University, Cairo, Egypt.ORCID 0000-0001-6949-8749

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPredicting the need for permanent pacemaker implantation (PPM) after transcatheter aortic valve implantation (TAVI) is crucial for procedural planning and patient counseling.

aimsTo evaluate whether left ventricular outflow tract (LVOT) morphology, specifically a tapered configuration, predicts conduction disturbances requiring PPM after TAVI using the Evolut self-expanding valve.

methodsThis retrospective multicenter study included patients undergoing TAVI with the self-expanding Evolut series. Pre-TAVI MSCT analysis included LVOT shape, membranous septum (MSep) length, and landing-zone calcification. Implantation depth (ID) was measured on final aortography.

resultsA total of 189 patients were included (age, 79.2 ± 6.8 years, 46% female, EuroSCORE II, 3.1 [1.9, 5.6]). Seventeen patients (9%) required PPM at 30 days. Patients with a tapered LVOT had a threefold higher PPM rate compared with those with a non-tapered configuration (21% vs. 7%, p = 0.015). PPM was significantly associated with tapered LVOT (OR: 4.2, p = 0.041), pre-existing right bundle branch block (RBBB) (OR: 12.4, p = 0.001), and deep valve implantation with a short MSep (OR: 16.4, p < 0.001).

conclusionTapered LVOT configuration, pre-existing RBBB, and deep implantation in the context of a short MSep are independent predictors of PPM following TAVI with the Evolut TAVI platform. Integrating LVOT configuration and MSep length into preprocedural planning may improve patient selection and prediction of PPM.

Indexed as

Aortic ValveAortic Valve StenosisArrhythmias, CardiacCardiac Pacing, ArtificialHeart Valve ProsthesisPacemaker, ArtificialTranscatheter Aortic Valve ReplacementAgedAged, 80 and overFemaleHumansMaleMultidetector Computed TomographyPredictive Value of TestsProsthesis DesignRetrospective Studiescomputed tomographyconduction disturbanceLVOTpacemaker implantationTAVI

Identifiers

PMID41527207
PMCPMC13043790

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.