ReviewInflammation and regeneration2026
Live imaging of skin immunity using two-photon microscopy: a short review.
Review in Inflammation and regeneration, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- The hierarchical stratum response system of organism to microgravity during spaceflight.Military Medical Research · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Two-photon excitation microscopy has become an important technique in dermatologic research, providing high-resolution imaging of living skin and its immune responses. Unlike conventional histology, two-photon microscopy allows direct observation of living tissues in real time at cellular resolution. This method enables the visualization of keratinocyte organization, skin appendages such as hair follicles and sebaceous glands, and the vascular, lymphatic, and neural networks within the dermis. It has also revealed dynamic immune processes in the skin. Clinical application is still limited by safety concerns and the high cost of equipment. Nonetheless, strategies based on autofluorescence, melanin scattering, and second harmonic generation (SHG) have been explored to visualize collagen and fibrosis in the dermis. This review summarizes the structural, functional, and translational aspects of two-photon skin imaging. We outline the technical principles, applications in animal and human studies, and potential implications for dermatologic research and clinical diagnosis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.