Evidence map›Paper›PMID 41527000›Full record

ArticlePilot and feasibility studies2026

Training caregivers to screen for relapse among children who have recovered from severe acute malnutrition: study protocol for a feasibility trial.

Clarisse Dah, Aimée Kimfuema, Mamadou Bountogo, Fanta Zerbo, Moussa Ouédraogo, Idrissa Kouanda, Ian Fetterman, Benjamin F Arnold, Elodie Lebas, Ali Sié and 1 more

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pilot and feasibility studies, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05932992 (Mother Screening for Relapse Using Mid-upper Arm Circumference Among Children Recovered From Severe Acute Malnutrition), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05932992 nacompletednot on this map

Mother Screening for Relapse Using Mid-upper Arm Circumference Among Children Recovered From Severe Acute Malnutrition

TypeinterventionalSponsorUniversity of California, San FranciscoRan2023 to 2024Enrolled400ConditionsSevere Acute MalnutritionArmsMother education on how to perform MUAC assessment
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Clarisse DahCentre de Recherche en Santé de Nouna, Nouna, Burkina Faso.
Aimée KimfuemaFrancis I Proctor Foundation, University of California, San Francisco, USA.
Mamadou BountogoCentre de Recherche en Santé de Nouna, Nouna, Burkina Faso.
Fanta ZerboCentre de Recherche en Santé de Nouna, Nouna, Burkina Faso.
Moussa OuédraogoCentre de Recherche en Santé de Nouna, Nouna, Burkina Faso.
Idrissa KouandaFrancis I Proctor Foundation, University of California, San Francisco, USA.
Ian FettermanFrancis I Proctor Foundation, University of California, San Francisco, USA.
Benjamin F ArnoldFrancis I Proctor Foundation, University of California, San Francisco, USA.
Elodie LebasFrancis I Proctor Foundation, University of California, San Francisco, USA.
Ali Sié *Centre de Recherche en Santé de Nouna, Nouna, Burkina Faso.
Catherine E Oldenburg *Francis I Proctor Foundation, University of California, San Francisco, USA. catherine.oldenburg@ucsf.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChildren with severe acute malnutrition (SAM) have a high risk of mortality and morbidity. After recovery from an initial episode of SAM, the risk of relapse can be high, although estimates vary across settings. Post-recovery surveillance for relapsed SAM in Burkina Faso consists of monthly clinic-based follow-up visits. However, adherence to the follow-up schedule can be variable, and children with missed surveillance visits may have delayed diagnoses of relapse. Here, we describe the protocol for a feasibility trial design to provide preliminary evidence to support the training of caregivers to screen for relapsed acute malnutrition using mid-upper arm circumference (MUAC) screening at home.

methodsThis feasibility trial will enroll 200 caregiver-child dyads in which the child has recovered in the past month from an episode of SAM in Boromo, Burkina Faso. Eligible children had an initial episode of SAM that they recovered from per Burkinabè guidelines (weight-for-height Z-score, WHZ ≥ -2 and/or MUAC ≥ 12.5 cm, depending on the admission criteria). Caregiver-child dyads are randomized to either weekly screening using a standard MUAC tape plus standard of care follow-up or standard of care alone, which consists of monthly clinic-based screening for relapse for 3 months. Caregiver-child dyads are followed for 6 months. Primary feasibility endpoints include acceptability, time for training, enrollment potential and refusals, adherence to the follow-up protocol, and adherence to the screening protocol. Clinical endpoints, measured to inform the design of a full-scale trial, include the proportion of children relapsing, anthropometric measurements at 6 months, hospitalization, and vital status. DISCUSSION: This feasibility trial will generate data to support the development and full-scale testing of an intervention to train caregivers to screen for relapsed acute malnutrition using MUAC.

trial registrationThis trial is registered at clinicaltrials.gov (NCT05932992), first posted 27 June 2023.

Indexed as

Mid-upper arm circumferenceRelapseScreeningSevere acute malnutritionWasting

Identifiers

PMID41527000
PMCPMC12888166

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.