Evidence map›Paper›PMID 41526973›Full record

ArticleJournal of cannabis research2026

Behavioral pharmacology of novel synthetic indazole, indole, and benzimidazole cannabinoids in rodents.

Ritu A Shetty, Rebecca D Hill, Jared A McDonald, Nathalie Sumien, Michael J Forster, Michael B Gatch

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cannabis research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ritu A ShettyDepartment of Pharmacology and Neuroscience, Center for Neuroscience Discovery, University of North Texas Health Science Center, 3500 Camp Bowie Blvd, Fort Worth, TX, 76107-2699, USA.
Rebecca D HillDepartment of Pharmacology and Neuroscience, Center for Neuroscience Discovery, University of North Texas Health Science Center, 3500 Camp Bowie Blvd, Fort Worth, TX, 76107-2699, USA.
Jared A McDonaldDepartment of Pharmacology and Neuroscience, Center for Neuroscience Discovery, University of North Texas Health Science Center, 3500 Camp Bowie Blvd, Fort Worth, TX, 76107-2699, USA.
Nathalie SumienDepartment of Pharmacology and Neuroscience, Center for Neuroscience Discovery, University of North Texas Health Science Center, 3500 Camp Bowie Blvd, Fort Worth, TX, 76107-2699, USA.
Michael J ForsterDepartment of Pharmacology and Neuroscience, Center for Neuroscience Discovery, University of North Texas Health Science Center, 3500 Camp Bowie Blvd, Fort Worth, TX, 76107-2699, USA.
Michael B GatchDepartment of Pharmacology and Neuroscience, Center for Neuroscience Discovery, University of North Texas Health Science Center, 3500 Camp Bowie Blvd, Fort Worth, TX, 76107-2699, USA. michael.gatch@unthsc.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSynthetic cannabinoids (SC) are created as alternatives to delta-9-tetrahydrocannabinol (∆

methodsThe eleven SC were tested for locomotor activity in Swiss-Webster mice and drug discrimination (DD) in Sprague-Dawley rats trained to discriminate ∆

resultsIn tests for locomotor depression, all the test compounds were more potent than ∆

conclusionIn summary, slight structural differences led to shifts in behavioral pharmacology outcomes in rodent models, which helped predict their potency relative to ∆ SUPPORT: Supported by NIDA contract N01DA-18-8936; N01DA-23-8936.

Indexed as

Abuse liabilityDelta-9-tetrahydrocannabinolDrug discriminationLocomotor activityRodentsSynthetic cannabinoids

Identifiers

PMID41526973
PMCPMC12888692

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.