Evidence map›Paper›PMID 41526749›Full record

ArticleDoklady. Biochemistry and biophysics2025

SAGA Transcription Coactivator Complex Is Associated with Histone Locus Body HLB.

Y A Yakusheva, S G Georgieva, M M Kurshakova

Abstract read
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In one paragraph

Article in Doklady. Biochemistry and biophysics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Y A YakushevaEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.
S G GeorgievaEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.
M M KurshakovaEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia. kursha@mail.ru.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The chromatin of histone genes is associated with specific nuclear biomolecular condensate called the histone locus body (HLB). HLB is the compartment where the transcription of histone genes and processing of their pre-mRNAs coordinated with the cell cycle take place. In this work, the transcriptional histone acetyltransferase coactivator complex SAGA is described as a component of the HLB. Specific subunits of the SAGA complex, Gcn5 and Sgf11 proteins, are present on the chromatin locus of the histone gene cluster and interact with known constant specific structural components of the HLB (Mxc, FLASH, and Mute proteins).

Indexed as

ChromatinHistonesTrans-ActivatorsAnimalsHistone AcetyltransferasesChromatinHistone AcetyltransferasesHistonesTrans-Activatorsbiomolecular condensateFLASHGcn5histone geneshistone mRNAHLBMuteMxcnuclear bodySAGASgf11

Identifiers

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.