Evidence map›Paper›PMID 41526654›Full record

ArticleCardiovascular and interventional radiology2026

Clinical Outcomes of Balloon-Only Venous Arterialization for Chronic Limb-Threatening Ischemia After Failed or Unfeasible Revascularization.

Tomonari Takagi, Mitsuyoshi Takahara, Yasutaka Yamauchi, Masashi Fukunaga, Hitoshi Anzai, Yuki Imoto, Kenji Ogata, Akira Miyamoto

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Cardiovascular and interventional radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tomonari TakagiCardiovascular Center, Takatsu General Hospital, 1-16-7 Mizonokuchi, Takatsu-Ku, Kawasaki-Shi, Kanagawa, 213-0001, Japan. burning_clutch@msn.com.
Mitsuyoshi TakaharaDepartment of Laboratory Medicine, The University of Osaka Graduate School of Medicine, Suita, Japan.
Yasutaka YamauchiCardiovascular Center, Takatsu General Hospital, 1-16-7 Mizonokuchi, Takatsu-Ku, Kawasaki-Shi, Kanagawa, 213-0001, Japan.
Masashi FukunagaDepartment of Cardiology, Morinomiya Hospital, Osaka, Japan.
Hitoshi AnzaiDepartment of Cardiology, SUBARU Health Insurance Ota Memorial Hospital, Ota, Japan.
Yuki ImotoDepartment of Cardiology, Fukuoka Wajiro Hospital, Fukuoka, Japan.
Kenji OgataDepartment of Cardiology, Miyazaki Medical Association Hospital, Miyazaki, Japan.
Akira MiyamotoCardiovascular Center, Takatsu General Hospital, 1-16-7 Mizonokuchi, Takatsu-Ku, Kawasaki-Shi, Kanagawa, 213-0001, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the efficacy and safety of balloon-only venous arterialization (BOVA) in patients with chronic limb-threatening ischemia (CLTI) and refractory ischemic ulcers after failed or no feasible conventional revascularization. MATERIALS AND

methodsThis multicenter retrospective cohort study included 56 limbs treated with BOVA at five Japanese institutions between May 2021 and December 2023. The primary efficacy outcome was 12-month complete wound healing, and the primary safety outcomes were 12-month freedom from major amputation and overall survival.

resultsThe cohort was high-risk: 76.8% had diabetes, 87.5% were on hemodialysis, 50.0% were Rutherford category 6, and 85.7% were Wound, Ischemia, and foot Infection stage 4. All pedal arteries were occluded in 80.4% of limbs. The 12-month complete wound healing rate was 45.5% (median time: 128 days). Freedom from major amputation, overall survival, and amputation-free survival were 83.5%, 54.6%, and 43.9%, respectively. Reintervention incidence was 5.58 procedures per person-year.

conclusionBOVA appears to be a feasible limb salvage strategy for patients with CLTI without conventional revascularization options. LEVEL OF EVIDENCE: Level 3b.

Indexed as

Angioplasty, BalloonIschemiaLimb SalvageAgedAged, 80 and overAmputation, SurgicalChronic Limb-Threatening IschemiaFemaleHumansJapanMaleMiddle AgedRetrospective StudiesTreatment OutcomeWound HealingDeep venous arterializationDesert footEndovascular treatmentEnd-stage renal disease

Identifiers

PMID41526654

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.