Evidence map›Paper›PMID 41526511›Full record

ArticleScientific reports2026

Antimicrobial photodynamic therapy using sodium iron chlorophyllin against drug-resistant Cutibacterium acnes from patients with acne vulgaris.

Buraya Mahajindawong, Chanat Kumtornrut, Pravit Asawanonda, Stephen J Kerr, Tanittha Chatsuwan, Einapak Boontaveeyuwat

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Buraya MahajindawongPhotodermatology unit, Division of dermatology, Department of medicine, King Chulalongkorn Memorial Hospital, The Thai Red Cross Society and Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand, 10330.
Chanat KumtornrutDivision of dermatology, Department of medicine, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, The Thai Red Cross Society, Bangkok, Thailand, 10330.
Pravit AsawanondaPhotodermatology unit, Division of dermatology, Department of medicine, King Chulalongkorn Memorial Hospital, The Thai Red Cross Society and Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand, 10330.
Stephen J KerrBiostatistics Excellence Centre, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Tanittha ChatsuwanDepartment of Microbiology, Faculty of medicine, Chulalongkorn University, Bangkok, Thailand, 10330. tanittha.c@chula.ac.th.
Einapak BoontaveeyuwatPhotodermatology unit, Division of dermatology, Department of medicine, King Chulalongkorn Memorial Hospital, The Thai Red Cross Society and Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand, 10330. einapak.b@chula.ac.th.

Funding

Ratchadapisek Sompoch Endowment Fund GA65/40
6 · The paper itself

Abstract

Antimicrobial resistance in Cutibacterium acnes is a growing concern, limiting treatment options for acne vulgaris (AV) and increasing the risk of opportunistic infections. Photodynamic therapy (PDT), using an effective photosensitizer (PS) and optimized light parameters, is a potent broad-spectrum antimicrobial strategy with minimal risk of resistance development. This study aimed to assess the efficacy of PDT using sodium iron chlorophyllin (CHL-Fe) as an in-house photosensitizer (CH-PDT) against 10 clinically isolated, drug-resistant C. acnes strains. The isolates, obtained from patients with mild to severe AV in a dermatology referral center, were resistant to one or more commonly prescribed antibiotics. CH-PDT was conducted using varying concentrations of CHL-Fe and red light (RL) fluences in laboratory conditions. A consistent bactericidal activity (> 3 log

Indexed as

Acne VulgarisAnti-Bacterial AgentsChlorophyllidesDrug Resistance, BacterialPhotochemotherapyPhotosensitizing AgentsPropionibacteriaceaeHumansMicrobial Sensitivity TestsRed LightAnti-Bacterial AgentsChlorophyllideschlorophyllinPhotosensitizing AgentsAcne vulgarisChlorophyllinCutibacterium acnesDrug resistancePhotodynamic therapy

Identifiers

PMID41526511
PMCPMC12877006

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.