Evidence map›Paper›PMID 41526417›Full record

ArticleScientific reports2026

Left atrial appendage closure with a novel nonpacifier device for stroke prevention in atrial fibrillation.

Ziyong Hao, Weifeng Zhang, Zhongping Ning, Chenyang Jiang, Lihong Wang, Jianjun Jiang, Heng Zhang, Cheng Wang, Xin Pan, Lisheng Jiang and 1 more

Abstract readMulticenter Study
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ziyong Hao *Department of Cardiology, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, 241 West Huaihai Road, Xuhui District, Shanghai, 200030, China.
Weifeng Zhang *Department of Cardiology, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, 241 West Huaihai Road, Xuhui District, Shanghai, 200030, China. charliezhang@126.com.
Zhongping NingDepartment of Cardiology, Zhoupu Hospital, Pudong New District, Shanghai, China.
Chenyang JiangDepartment of Cardiology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Lihong WangDepartment of Cardiology, Zhejiang Provincial People's Hospital, Hangzhou, Zhejiang, China.
Jianjun JiangDepartment of Cardiology, Taizhou Hospital of Zhejiang Province, Taizhou, Zhejiang, China.
Heng ZhangDepartment of Cardiology, The First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui, China.
Cheng WangDepartment of Cardiology, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, 241 West Huaihai Road, Xuhui District, Shanghai, 200030, China.
Xin PanDepartment of Cardiology, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, 241 West Huaihai Road, Xuhui District, Shanghai, 200030, China.
Lisheng JiangDepartment of Cardiology, Shanghai East Hospital, Tongji University School of Medicine, 150 Jimo Road, Pudong New District, Shanghai, 200120, China. jiangls1025@163.com.
Ben HeDepartment of Cardiology, Shanghai East Hospital, Tongji University School of Medicine, 150 Jimo Road, Pudong New District, Shanghai, 200120, China.

Funding

National Key R&D Program of China 2024YFC2421200National Natural Science Foundation of China 82400403Three-year action plan project to promote clinical skills and clinical innovation ability of Shanghai municipal hospitals SHDC2020CR1039B
6 · The paper itself

Abstract

Percutaneous left atrial appendage (LAA) closure is a viable alternative to chronic oral anticoagulation for reducing thromboembolic risk in non-valvular atrial fibrillation (AF) patients. To date, no clinical data have been published on the novel nonpacifier LAA closure device evaluated herein. We therefore conducted a prospective, non-randomized, multi-center registry across 6 Chinese hospitals to provide the first clinical evidence of its safety and effectiveness among AF patients with an increased risk of stroke, using performance goals to assess 6-month effective LAA closure and 12-month ischemic stroke incidence. Among 187 enrolled patients (mean age 67.7 ± 7.5 years; mean CHA

Indexed as

Atrial AppendageAtrial FibrillationLeft Atrial Appendage ClosureStrokeAgedFemaleHumansMaleMiddle AgedProspective StudiesRegistriesTreatment OutcomeIschemic strokeLeft atrial appendage closureMulti-center registryNovel devicePerformance goalPeri-device leak

Identifiers

PMID41526417
PMCPMC12858888

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.