ArticleScientific data2026
The Ontology of Adverse Events in 2025.
Article in Scientific data, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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0 citing papers in PubMed.
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Authors and funding
6 authors.
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Abstract
The Ontology of Adverse Events (OAE) was launched in 2011 to define, standardize and integrate various adverse events (AEs) arising after medical interventions. The terminological framework of OAE has undergone consistent expansion since its inception, driven by its successful implementation in numerous AE investigations. In this paper, we document substantial ontological extensions addressing patient anatomic regions and clinical manifestations, encompassing symptoms, physical signs, and pathological processes. Current statistical analysis reveals that OAE has 10,829 formally defined terms with unique identifiers. Compared to the 3,088 ontology terms included in the last OAE publication in 2014, 7,741 new terms have been added to OAE, which represents significant progress of the ontology in clinical granularity and domain coverage. The OAE framework enables structured representation of critical determinants influencing clinical outcomes, including but not limited to administration routes, dosage parameters, and demographic variables such as patient age. Through its standardized semantic architecture, OAE provides an integrative platform for cross-disciplinary analysis of AE patterns, etiological factors, and outcome trajectories in clinical interventions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.