Evidence map›Paper›PMID 41526368›Full record

ArticleNature communications2026

Atomically precise ligand engineering of gold nanoparticles via interphase mass transfer.

Bihan Zhang, Feng Xiao, Xiaorong Song, Moshuqi Zhu, Qiaofeng Yao, Jianping Xie

Abstract read
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Bihan Zhang *Department of Chemical and Biomolecular Engineering, National University of Singapore, Singapore, Singapore.
Feng Xiao *Guangdong Provincial Key Laboratory of Advanced Biomaterials, Shenzhen Key Laboratory of Smart Healthcare Engineering, Department of Biomedical Engineering, Southern University of Science and Technology, Shenzhen, Guangdong, PR China.
Xiaorong SongMOE Key Laboratory for Analytical Science of Food Safety and Biology & State Key Laboratory of Photocatalysis on Energy and Environment, College of Chemistry, Fuzhou University, Fuzhou, China.
Moshuqi ZhuJoint School of National University of Singapore and Tianjin University, International Campus of Tianjin University, Binhai New City, Fuzhou, PR China. zhumoshuqi@tju.edu.cn.
Qiaofeng YaoKey Laboratory of Organic Integrated Circuits, Ministry of Education & Tianjin Key Laboratory of Molecular Optoelectronic Sciences, Department of Chemistry, School of Science, Tianjin University, Tianjin, China. qfyao@tju.edu.cn.ORCID http://orcid.org/0000-0002-5129-9343
Jianping XieDepartment of Chemical and Biomolecular Engineering, National University of Singapore, Singapore, Singapore. chexiej@nus.edu.sg.ORCID http://orcid.org/0000-0002-3254-5799

Funding

Ministry of Education - Singapore (MOE) A-8000054-01-00National Natural Science Foundation of China (National Science Foundation of China) 22371204National Natural Science Foundation of China (National Science Foundation of China) 92461304
6 · The paper itself

Abstract

Precise surface engineering of gold nanoclusters (Au NCs) is critical for bioimaging. However, conventional methods often compromise the structural integrity of Au NCs or result in uncontrolled ligand distribution due to rapid reaction kinetics and etching side reactions. Herein, we develop an interphase-assisted ligand exchange method, which leverages mass transfer resistance between immiscible phases to precisely control the mass transfer of ligands. This approach significantly suppresses side etching while maintaining exchange kinetics, enabling high-yield, structure-preserving substitution of diverse thiol ligands on Au NCs. By systematically introducing p-aminothiophenol (p-ATP) ligands, we reveal that increasing p-ATP density on Au

Indexed as

GoldMetal NanoparticlesAnimalsFemaleKineticsLigandsLiverMiceMice, Inbred BALB CMice, NudeSulfhydryl CompoundsTissue DistributionGoldLigandsSulfhydryl Compounds

Identifiers

PMID41526368
PMCPMC12905179

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.