ArticlePloS one2026
Cohort profile: The Bristol IVF Study- A longitudinal study of women, their partners and treatment outcomes following assisted reproductive technologies.
Article in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Article
Corrections and comments
- Erratum issued
Authors and funding
11 authors.
Funding
Abstract
backgroundThe Bristol IVF Study (BRIST-IVF) is a longitudinal clinical cohort, established to determine factors related to successful live birth and other outcomes following conception by assisted reproductive technologies (ART). This cohort profile describes recruitment, data collection and planned research.
methodsThe study gathered comprehensive sociodemographic, lifestyle, anthropometric, and clinical data from women and their partners before and during treatment, as well as during pregnancy and after birth. Biological samples, including blood, urine, and saliva, were collected at initial recruitment and at pregnancy clinics, with cord blood and placental tissue obtained at birth. Participants consented to NHS record linkage, allowing access to pregnancy and birth outcomes from obstetric notes. Data collection during pregnancy and after birth followed the same protocols as a naturally conceived cohort, the second generation of the Avon Longitudinal Study of Parents and Children (ALSPAC-G2).
resultsBetween 3rd September 2019 and 30th June 2023, 502 couples or single women were recruited (967 individuals in total). Of these, 490 women underwent 1,055 ART treatment cycles during the study follow-up (up to 31st March 2024). Recruited women had a mean age of 35.8 years (SD = 4.4) and a mean BMI of 25.1 (SD = 4.4). At the time of recruitment, 251 women (50%) had never been pregnant, and 374 (75%) had not had a previous live birth. Women and their partners with a confirmed viable pregnancy at a scan performed at 7 weeks of gestation were invited to participate in the pregnancy follow-up study, with 305 women (for 324 pregnancies) invited. Data were collected from pregnancy questionnaires (n = 246, 76%), pregnancy clinic data (n = 119, 37%), and birth questionnaires (n = 223, 69%). Collection of obstetric data from health records is ongoing.
conclusionThe BRIST-IVF cohort enables novel research into the predictors and consequences of ART conception, with comparison to ALSPAC-G2.
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Registered trials
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