Evidence map›Paper›PMID 41525207›Full record

ArticleMicrobiology (Reading, England)2026

Using a 'one strain-many compounds' approach to screen a collection of diverse fungi from Aotearoa New Zealand for antibacterial activity against

Shara van de Pas, Melissa M Cadelis, Alexander B J Grey, Jessica M Flemming, Duckchul Park, Thomas Lumley, Bevan S Weir, Brent R Copp, Siouxsie Wiles

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microbiology (Reading, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Shara van de PasBioluminescent Superbugs Lab, Department of Molecular Medicine and Pathology, Waipapa Taumata Rau - University of Auckland, Auckland, New Zealand.
Melissa M CadelisBioluminescent Superbugs Lab, Department of Molecular Medicine and Pathology, Waipapa Taumata Rau - University of Auckland, Auckland, New Zealand.
Alexander B J GreyBioluminescent Superbugs Lab, Department of Molecular Medicine and Pathology, Waipapa Taumata Rau - University of Auckland, Auckland, New Zealand.
Jessica M FlemmingSchool of Chemical Sciences, Waipapa Taumata Rau - University of Auckland, Auckland, New Zealand.
Duckchul ParkBioeconomy Science Institute, Manaaki Whenua - Landcare Research Group, Auckland, New Zealand.
Thomas LumleyDepartment of Statistics, Waipapa Taumata Rau - University of Auckland, Auckland, New Zealand.
Bevan S WeirBioeconomy Science Institute, Manaaki Whenua - Landcare Research Group, Auckland, New Zealand.
Brent R CoppSchool of Chemical Sciences, Waipapa Taumata Rau - University of Auckland, Auckland, New Zealand.
Siouxsie WilesBioluminescent Superbugs Lab, Department of Molecular Medicine and Pathology, Waipapa Taumata Rau - University of Auckland, Auckland, New Zealand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is an urgent need to identify new chemical compounds with novel modes of action to help manage the antimicrobial resistance crisis. Fungi are prolific producers of secondary metabolites, including those with antimicrobial properties, and contain biosynthetic gene clusters that awaken only under certain growth conditions. In recent years, a wealth of novel fungal biosynthetic pathways and compounds have been identified, suggesting fungi remain a viable source for developing new antimicrobials. The International Collection of Microorganisms from Plants (ICMP) contains thousands of fungi and bacteria primarily sourced from Aotearoa New Zealand. Here, we report the results of our efforts to screen 32 fungal ICMP isolates for activity against

Indexed as

Anti-Bacterial AgentsEscherichia coliFungiCulture MediaNew ZealandPhylogenyAnti-Bacterial AgentsCulture Mediaantibacterialantroalbol HEscherichia colifungimerulin Aminimum inhibitory concentrationscreeningsteperoxide A

Identifiers

PMID41525207
PMCPMC12825035

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.