Evidence map›Paper›PMID 41525033›Full record

SynthesisUpdates in surgery2026

Human Factors and Quantitative Data: Diverging Perspectives on ICG use in Emergency Bowel Surgery -  A systematic literature review.

Ankita Kulkarni, Camy Sheth, Nikhil Pawa

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Updates in surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ankita KulkarniWest Middlesex University Hospital, Chelsea and Westminster Hospital NHS Foundation Trust, London, UK. ankita.kulkarni2@nhs.net.ORCID http://orcid.org/0009-0007-6996-5141
Camy ShethWest Middlesex University Hospital, Chelsea and Westminster Hospital NHS Foundation Trust, London, UK.ORCID http://orcid.org/0009-0000-4007-4408
Nikhil PawaWest Middlesex University Hospital, Chelsea and Westminster Hospital NHS Foundation Trust, London, UK.ORCID http://orcid.org/0000-0003-2122-0830

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Indocyanine Green (ICG) fluorescence imaging is increasingly used in emergency bowel surgery to assess intestinal perfusion. While literature reports high technical efficacy, intraoperative interpretation remains variable. This systematic review explores how cognitive and systemic human factors influence ICG's perceived effectiveness, compared to reported quantitative outcomes. A systematic search of PubMed and Embase identified 31 original studies from 266 screened articles. Qualitative synthesis was guided by ENTREQ principles. Bias identification followed a thematic approach using cognitive bias categories based on established clinical decision-making frameworks. ICG was reported to influence surgical decision-making in 302 of 308 cases. However, discrepancies between fluorescence findings and clinical actions occurred in 38.3% of cases. Common cognitive patterns included confirmation and anchoring bias, overconfidence in fluorescence interpretation, and reliance on ICG to support pre-established surgical decisions. Systemic limitations included lack of interdisciplinary input, case-report bias, and absence of standardized interpretation protocols. These were analyzed across a full article-by-article bias matrix and summarized by domain and sentiment. ICG is not solely a diagnostic tool, but a cognitive interface shaped by time pressure, decision momentum, and human interpretation. Rather than providing objective certainty, ICG often reinforces existing clinical judgments. Addressing bias-awareness and integrating interdisciplinary frameworks may enhance interpretive consistency and improve patient outcomes. These findings call for greater cognitive standardization in the intraoperative use of ICG during emergency surgery.

Indexed as

Digestive System Surgical ProceduresEmergenciesIndocyanine GreenIntestinesOptical ImagingClinical Decision-MakingHumansIndocyanine GreenBowel ischemiaCognitive biasEmergency general surgeryFluorescence angiographyHuman factorsIndocyanine green

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.