Evidence map›Paper›PMID 41524756›Full record

Trial reportEuropean journal of applied physiology2026

Ischemic preconditioning with active reperfusion does not improve high-intensity intermittent exercise in youth team sport players.

Gustavo R Mota, Izabela A Santos, Anderson Luiz Rodrigues, Bernardo N Ide, Tom Citherlet, Jeffer E Sasaki, Moacir Marocolo

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in European journal of applied physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Gustavo R MotaExercise Science, Health and Human Performance Research Group, Department of Sport Sciences, Institute of Health Sciences, Federal University of Triângulo Mineiro, Uberaba, Brazil. gustavo.mota@uftm.edu.br.ORCID http://orcid.org/0000-0002-6109-0658
Izabela A SantosExercise Physiology in Health and Human Performance Research Group, Department of Physical Education, University of Uberaba (UNIUBE), Uberaba, Brazil.ORCID http://orcid.org/0000-0003-3425-0326
Anderson Luiz RodriguesExercise Science, Health and Human Performance Research Group, Department of Sport Sciences, Institute of Health Sciences, Federal University of Triângulo Mineiro, Uberaba, Brazil.
Bernardo N IdeExercise Science, Health and Human Performance Research Group, Department of Sport Sciences, Institute of Health Sciences, Federal University of Triângulo Mineiro, Uberaba, Brazil.ORCID http://orcid.org/0000-0003-4057-0051
Tom CitherletInstitute of Sport Sciences, University of Lausanne, Lausanne, Switzerland.ORCID https://orcid.org/0009-0008-4492-0227
Jeffer E SasakiExercise Science, Health and Human Performance Research Group, Department of Sport Sciences, Institute of Health Sciences, Federal University of Triângulo Mineiro, Uberaba, Brazil.ORCID http://orcid.org/0000-0002-2083-4104
Moacir MarocoloIntegrated Laboratory of Physiology and Performance (LABIFID), Department of Biophysics and Physiology, Federal University of Juiz de Fora, Juiz de Fora, Brazil.ORCID https://orcid.org/0000-0002-7715-2534

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe investigated whether an active protocol of ischemic preconditioning (IPC-A) would improve high-intensity intermittent exercise performance in youth team sport players.

methodsFifteen male amateur team sport players (15.5 ± 0.5 yrs) attended four different preconditioning sessions before the YoYo Intermittent Recovery Test level 1 (YYIR1) interspersed by seven days in a counterbalanced randomized cross-over design. IPC protocol consisted of three cycles of 5 min occlusion (220 mmHg) and 5 min reperfusion (0 mmHg) in both thighs. SHAM was similar to the IPC protocol, but 'occlusion' pressure was set up at 20 mmHg. Active protocols (IPC-A/ SHAM-A) were similar to the IPC/SHAM, but participants exercised (intermittent run) during the 'reperfusion' phases instead of resting. Six minutes after the protocol, the participants performed the YYIR1.

resultsThe distance covered in the YYIR1 did not differ (p = 0.46) among the protocols: IPC (917 ± 204 m) vs. IPC-A (931 ± 211 m) vs. SHAM (968 ± 201 m) vs. SHAM-A (933 ± 204 m). Blood lactate concentration, and mean heart rate did not differ either (p > 0.05) among the protocols.

conclusionsActive ischemic preconditioning involving exercise during reperfusion phase does not improve high-intensity intermittent exercise performance nor alter physiological or perceptual responses in youth team sport players.

Indexed as

Athletic PerformanceHigh-Intensity Interval TrainingIschemic PreconditioningAdolescentCross-Over StudiesHeart RateHumansLactic AcidMaleLactic AcidBasketballBlood flowEnduranceErgogenicIschemiaSoccer

Identifiers

PMID41524756
PMCPMC13236811

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.