ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2026
The OCT-RiSK model: predicting early macular reattachment after rhegmatogenous retinal detachment repair.
Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeTo develop and validate the OCT-RiSK (Optical Coherence Tomography-based Retinal Integrity and Surgical Knowledge) scoring model for predicting early macular anatomical outcomes following rhegmatogenous retinal detachment (RRD) repair.
methodsThis retrospective, single-center study included eyes with fovea-off primary RRD that underwent pars plana vitrectomy (PPV), scleral buckle (SB), or pneumatic retinopexy between January 2020 and December 2024 at a tertiary eye hospital in India. Preoperative OCT scans were analyzed for eleven predefined macular biomarkers, and 4-week postoperative OCT images were evaluated for macular reattachment. Suboptimal macular reattachment was defined as persistent macular subretinal fluid on 4-week OCT. An elastic-net logistic regression model incorporating OCT biomarkers and surgical technique was developed and validated to predict early macular attachment. Based on statistically significant predictors, a non-weighted OCT-RiSK score (+ 1 point per variable) was derived, stratifying eyes into low- and high-risk groups for suboptimal reattachment.
resultsA total of 1,491 eyes (median age 55 years) were analyzed. Suboptimal anatomical recovery occurred in 23.9% (n = 357). Four OCT biomarkers-absence of posterior vitreous dots, intraretinal cysts, and outer retinal corrugations, and presence of photoreceptor loss-along with SB surgery were identified as independent predictors of suboptimal macular reattachment. The OCT-RiSK model achieved an overall accuracy of 84.3%, with higher OCT-RiSK scores (> 2) significantly associated with suboptimal outcomes (p < 0.001).
conclusionThe OCT-RiSK scoring system provides a practical, data-driven framework for predicting early postoperative macular outcomes, supporting personalized surgical planning, patient counselling, and risk stratification in RRD management.
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