ArticleChemical communications (Cambridge, England)2026
A 2nd-generation scalable synthesis of the HIV-1 entry inhibitor CJF-III-288 enabled by photoredox catalysis.
Article in Chemical communications (Cambridge, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
The development and optimization of a 2nd-Generation process synthesis for the human immunodeficiency virus-1 entry inhibitor CJF-III-288 bis-trifloroacetate salt 1 is reported. The route eliminates the use of noble metals, decreases the step count nearly by half, and increases the overall yield tenfold.
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