ReviewArthritis care & research2026
Conflicts of Interest Reporting in Trials and Guidelines Addressing Glucocorticoid Injections for Knee Osteoarthritis.
Review in Arthritis care & research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis study aimed to characterize conflict of interest disclosure practices in trials and guidelines recommending glucocorticoid injections for knee osteoarthritis.
methodsThree databases (CINAHL, Ovid MEDLINE ALL, and Embase) were queried for randomized controlled trials from database inception to April 2025 that assessed glucocorticoid injection treatment effect for knee osteoarthritis. Clinical practice guidelines were retrieved from a recent systematic review. Study details, authors, affiliations, and conflict of interest disclosures were extracted. Transparency and appropriateness with addressing disclosures were assessed for every article, and disclosures were examined and compared with three national public conflict of interest disclosure databases. All conflicts were categorized and proportions calculated.
resultsSeventy-five trials and 14 guidelines were included. Twenty-nine percent of trials (n = 22) and 14.3% of guidelines (n = 2) had no conflict of interest statement. Ten trials (13.3%) and six guidelines (42.9%) reported a conflict of interest for at least one author. Eleven trials (14.7%) and six guidelines (42.9%) had discrepancies between disclosures in articles and reports in public databases. Forty-three trial authors (34.1%) and 19 (9.4%) guideline authors had discrepancies between disclosures in the articles and public databases.
conclusionConflict of interest reporting practices in trials and guidelines assessing effectiveness of glucocorticoid injections for knee osteoarthritis are poor, with a lack of transparency. Quality and thoroughness with reporting conflicts of interest is necessary to best understand industry influence on treatment recommendations.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.