ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2026
Receptor-Dependent and -Independent Effects of Hemin on Platelet Plasma Membrane Disintegration.
Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Receptor-Dependent and -Independent Effects of Hemin on Platelet Plasma Membrane Disintegration.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Microhemorrhages are an underestimated aspect in the pathophysiology of vulnerable plaques and aneurysms. Erythrocyte liberation within hemorrhages leads to extracellular hemoglobin accumulation and iron-containing hemin generation. Hemin induces platelet activation, thrombosis, and ferroptosis-mediated destruction of platelet membranes through GPVI/CLEC-2 signaling. Hemin-toxicity results in destruction of platelet membranes, which is caused by ferroptosis, a non-apoptotic cell death. Antiplatelet drugs have limited effect on hemin-induced activation. We evaluated the effect of hemin on platelet function using light transmission aggregometry and multipanel flow cytometry. We found that P2Y
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Registered trials
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