ArticleJournal of the Turkish German Gynecological Association2026
Conventional in vitro fertilization at the age of fourties
Article in Journal of the Turkish German Gynecological Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: Contrary to international guidelines, intracytoplasmic injection (ICSI) has increasingly been applied to a widening range of indications. The aim of this study is to present our experience with conventional in vitro fertilization (C-IVF) in women in their forties and to contribute to the ongoing debate on whether advanced maternal age should be considered an indication for preferring ICSI. Material and Methods: We analyzed cases of non-male factor infertility in women aged ≥40 years. The primary outcome measures were fertilization rate, implantation rate, live birth rate, and miscarriage rate. Results: The cohort included 204 patients with a mean age of 42.30±1.97 years, a mean antral follicle count of 4.65±2.60, body mass index of 25.80±4.54 kg/m Conclusion: Fertilisation, implantation, live birth and miscarriage rates after C-IVF are satisfactory for women ≥40 years of age. Given its lower cost, ease of application and comparable clinical outcomes, C-IVF should be considered the preferred method of fertilisation in advanced-age patients.
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