Evidence map›Paper›PMID 41524036›Full record

ReviewJournal of arrhythmia2026

Cardiac Resynchronization Therapy: Reconsidering Its Essence as a Treatment for Electrical Dyssynchrony in Heart Failure.

Michio Ogano, Yu-Ki Iwasaki, Jun Tanabe, Wataru Shimizu, Kuniya Asai

Abstract readReview
In one paragraph

Review in Journal of arrhythmia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Michio OganoDepartment of Cardiovascular Medicine Shizuoka Medical Center Shimizu Japan.ORCID https://orcid.org/0000-0003-0869-3078
Yu-Ki IwasakiDepartment of Cardiovascular Medicine Nippon Medical School Bunkyo Tokyo Japan.ORCID https://orcid.org/0000-0001-8783-1365
Jun TanabeDepartment of Cardiovascular Medicine Shizuoka Medical Center Shimizu Japan.
Wataru ShimizuDepartment of Cardiovascular Medicine Nippon Medical School Bunkyo Tokyo Japan.
Kuniya AsaiDepartment of Cardiovascular Medicine Nippon Medical School Bunkyo Tokyo Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiac resynchronization therapy (CRT) essentially targets electrical dyssynchrony, one of the key drivers in heart failure (HF). Its efficacy depends on both the quality (QRS morphology) and quantity (QRS duration) of dyssynchrony, requiring individualized patient selection. While drug therapy for HF has a limited effect on this substrate, early implantation of CRT can prevent irreversible remodeling and facilitate optimization of medical therapy. CRT should be recognized as an essential component within a comprehensive strategy for HF management in patients with appropriate indications.

Indexed as

cardiac resynchronization therapyelectrical dyssynchronyheart failureleft ventricular lead positioningQRS duration

Identifiers

PMID41524036
PMCPMC12789663

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.