ArticleCirculation reports2026
Multidimensional Frailty and Mortality in Transcatheter Aortic Valve Implantation Patients - Prognostic Value of the Kihon Checklist.
Article in Circulation reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Association between frailty and postoperative delirium after transcatheter aortic valve replacement: a meta-analysis.Frontiers in psychiatry · 2026Pooled it
- Clinical Course and Mid- to Long-Term Outcome of Chimney Stenting in Patients With Small Anatomy Undergoing Self-Expanding Transcatheter Aortic Valve Implantation.Circulation reports · 2026Article
- Skeletal Muscle Oxygenation During Exercise and Its Association With Early Improvement in Exercise Tolerance After Transcatheter Aortic Valve Implantation.Circulation reports · 2026Article
- Effect of Comprehensive Outpatient Cardiac Rehabilitation on All-Cause Mortality After Transcatheter Aortic Valve Implantation.Circulation reports · 2026Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Frailty is a crucial factor in the prognoses of patients who undergo transcatheter aortic valve implantation (TAVI); however, comprehensive assessments of this parameter are not frequently performed in this regard. This study evaluated the prognostic value of the Kihon Checklist (KCL), which covers physical, cognitive, and social domains, for patients receiving TAVI. Methods and Results: We retrospectively analyzed data from 986 patients who underwent elective TAVI between May 2017 and September 2022. Frailty was classified according to the KCL as non-frail (for scores of 0-3), pre-frail (4-7), or frail (≥8). The primary outcome measure was all-cause mortality following discharge. Kaplan-Meier, Cox regression, and classification and regression tree (CART) analyses were used. Of the overall patient cohort, 47.4% were classified as frail. Over a mean follow-up period of 968±578 days, 18.1% died. Frailty was significantly associated with higher mortality (adjusted hazard ratio 1.771; 95% confidence interval 1.096-2.862; P<0.02). Impaired socialization and physical function were also found to represent independent predictors of mortality. CART identified socialization as the primary node in the risk stratification. Conclusions: Preoperative frailty, as defined by the KCL, was found to be independently associated with mortality after TAVI. Social and physical domains were also found to have strong prognostic relevance in this context.
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