Evidence map›Paper›PMID 41523780›Full record

ArticleWorld journal of experimental medicine2025

Burden of multi-drug-resistant organisms in a tertiary healthcare institute in North India: Implications for regional public health.

Harshita Singh, Ananya Ashwairya Patel, Pradeep Pandy, Balram Ji Omar, Amber Prasad, Vanya Singh, Prakhar Sharma, Mukesh Bairwa, Rakesh Kumar Sihag, Ashutosh Tiwari and 17 more

Abstract read
In one paragraph

Article in World journal of experimental medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors.

Harshita SinghDivision of Internal Medicine, All India Institute of Medical Sciences, Rishikesh, Rishikesh 249203, India.
Ananya Ashwairya PatelDivision of Internal Medicine, All India Institute of Medical Sciences, Rishikesh, Rishikesh 249203, India.
Pradeep PandyDivision of Internal Medicine, All India Institute of Medical Sciences, Rishikesh, Rishikesh 249203, India.
Balram Ji OmarDepartment of Microbiology, All India Institute of Medical Sciences, Rishikesh 249203, India.
Amber PrasadDepartment of Microbiology, All India Institute of Medical Sciences, Rishikesh 249203, India.
Vanya SinghDepartment of Microbiology, All India Institute of Medical Sciences, Rishikesh 249203, India.
Prakhar SharmaDepartment of Pulmonary Medicine, All India Institute of Medical Sciences, Rishikesh 249203, India.
Mukesh BairwaDivision of Internal Medicine, All India Institute of Medical Sciences, Rishikesh, Rishikesh 249203, India.
Rakesh Kumar SihagDepartment of Neurosurgery, All India Institute of Medical Sciences, Rishikesh 249203, India.
Ashutosh TiwariDepartment of Neurology, All India Institute of Medical Sciences, Rishikesh 249203, India.
Deepak RajputDepartment of General Surgery, All India Institute of Medical Sciences, Rishikesh 249203, India.
Manish KulshresthaDepartment of General Surgery, All India Institute of Medical Sciences, Rishikesh 249203, India.
Sandeep SainiDepartment of Nephrology, All India Institute of Medical Sciences, Rishikesh 249203, India.
Ajay KumarDepartment of Trauma Surgery, All India Institute of Medical Sciences, Rishikesh 249203, India.
Bhaskar SarkarDepartment of Trauma Surgery, All India Institute of Medical Sciences, Rishikesh 249203, India.
Bhanu DuggalDepartment of Cardiology, All India Institute of Medical Sciences, Rishikesh 249203, India.
Ankit AgarwalDepartment of Anesthesia and Critical Care, All India Institute of Medical Sciences, Rishikesh 249203, India.
Nidhi KaeleyDepartment of Emergency Medicine, All India Institute of Medical Sciences, Rishikesh 249203, India.
Gaurav DhingraDepartment of Hematology and Medical Oncology, All India Institute of Medical Sciences, Rishikesh 249203, India.
Prakash MahalaDepartment of Nursing Services, All India Institute of Medical Sciences, Rishikesh 249203, India.
Vishnu YesodharanDepartment of Nursing Services, All India Institute of Medical Sciences, Rishikesh 249203, India.
Himanshu ChauhanDepartment of Nursing Services, All India Institute of Medical Sciences, Rishikesh 249203, India.
Deepa KumariDepartment of Nursing Services, All India Institute of Medical Sciences, Rishikesh 249203, India.
Suman ChoudharyDepartment of Nursing Services, All India Institute of Medical Sciences, Rishikesh 249203, India.
Ashok K SharmaDepartment of Nursing Services, All India Institute of Medical Sciences, Rishikesh 249203, India.
Rakhi YadavDepartment of Nursing Services, All India Institute of Medical Sciences, Rishikesh 249203, India.
Prasan Kumar PandaDivision of Internal Medicine, All India Institute of Medical Sciences, Rishikesh, Rishikesh 249203, India. motherprasanna@rediffmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAntimicrobial resistance (AMR) is an escalating global health threat, disproportionately impacting low-income and middle-income countries like India. The rise of multidrug-resistant organisms (MDROs) complicates treatment, increases healthcare costs, and contributes to higher morbidity and mortality. In India, factors such as antibiotic misuse, over-the-counter availability, and self-medication have exacerbated this crisis. Despite the urgency, regional data on MDRO prevalence remains limited.

aimTo assess the burden and distribution of MDRO infections identified at a tertiary healthcare institute in North India.

methodsThis cross-sectional study analyzed inpatient data from All India Institute of Medical Sciences (AIIMS) Rishikesh using the E-hospital database from May 2021 to February 2024, except 2022. All inpatients with culture-confirmed MDRO infections were included. Patient charts and discharge summaries were reviewed. Data analysis was performed using Jamovi software, with descriptive statistics summarizing demographics. The

resultsThis study included 820 participants having 1106 MDROs. The majority of patients were aged 35-64 years, with a male predominance (57.6%). Most cases were from Uttar Pradesh (49.1%) and Uttarakhand (47.6%), with Bijnor and Haridwar districts reporting the highest burden from their respective states.

conclusionThis study highlights the burden of MDROs among patients at AIIMS Rishikesh, with

Indexed as

Antimicrobial stewardshipInfection controlKlebsiella pneumoniaeMulti-drug resistancePublic health

Identifiers

PMID41523780
PMCPMC12781631

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.