Evidence map›Paper›PMID 41523613›Full record

ArticleScientifica2025

Metabolites Evaluation, Cytotoxicity, and Teratogenicity Analysis of Selected Medicinal Plants.

Mary Jhane G Valentino, Tutik Sri Wahyuni

Abstract read
In one paragraph

Article in Scientifica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Mary Jhane G ValentinoAirlangga Post Doctoral Fellow, Universitas Airlangga, Surabaya, Indonesia, unair.ac.id.ORCID https://orcid.org/0000-0003-3814-5478
Tutik Sri WahyuniDepartment Pharmaceutical Science, Faculty of Pharmacy, Airlangga University, Surabaya, Indonesia, unair.ac.id.ORCID https://orcid.org/0000-0003-2049-7774

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The study determined the cytotoxicity and teratogenicity of 28 species of medicinal plants. The phytochemical properties and antioxidant activity were also evaluated. Plant materials were extracted using ethanol as solvent. Brine shrimp assay was performed for cytotoxicity test and zebra fish embryo-based teratogenicity testing. The phytochemical constituents were detected using thin-layer chromatography, while the total phenolics and antioxidant activity were determined using the Folin-Ciocalteu method and DPPH free radical scavenging assay, respectively. Results of phytochemical screening revealed the presence of 12 phytochemicals in the selected medicinal plants, which include essential oils, triterpenes, phenols, fatty acids, sugar, anthraquinones, coumarins, anthrone, tannins, flavonoids, steroids, and alkaloids. Total phenolic content which ranges from 125.45 to 568.99 GAE/g and antioxidant activity of 40.25%-82.56% were recorded from

Indexed as

cytotoxicitymedicinal plantsphytochemicalsteratogenicity

Identifiers

PMID41523613
PMCPMC12782329

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.