Evidence map›Paper›PMID 41523526›Full record

ArticleCureus2025

Panhypopituitarism Secondary to a Central Nervous System Germinoma.

Somia Hassanes, Eboh Cecil, Betsy Francis

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Somia HassanesMedicine, University Hospitals Sussex NHS Foundation Trust, Chichester, GBR.
Eboh CecilMedicine, University Hospitals Sussex NHS Foundation Trust, Chichester, GBR.
Betsy FrancisMedicine, University Hospitals Sussex NHS Foundation Trust, Chichester, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Germ cells are the reproductive cells in a foetus which later develop into sperm in the testicles or unfertilized eggs in the ovaries. They occur in the gonads (testis and ovaries) but can also occur elsewhere in the body, including intracranially. In this case, these tumours can affect the function of the pituitary gland, causing different endocrinological conditions. Understanding the aetiology, classification, and clinical behaviour of germ cell tumours is essential for timely diagnosis, appropriate treatment, and prognostication, given the spectrum of entities encompassed by this group and their variable therapeutic sensitivity and outcomes. This case report highlights the importance of considering intracranial germ cell tumours in a young adult admitted with endocrinopathy as the first presentation.

Indexed as

central diabetes insipidus (cdi)germinomahypopituitarism (hp)intracranial germ cell tumorspineal germinomasuprasellar tumour

Identifiers

PMID41523526
PMCPMC12785503

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.