ArticleCureus2025
A Life-Threatening Case of Severe Leptospirosis in Wales, UK: Recognising Severe Disease in Non-endemic Settings.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
4 authors.
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Abstract
Leptospirosis is an infectious disease that is uncommonly seen in the United Kingdom. It is typically associated with occupational exposure among sewage workers, farmers, veterinarians and abattoir employees. The illness is known by other terms such as seven-day fever, haemorrhagic fever and Weil's disease. The prevalence of leptospirosis outside of the United Kingdom is well documented, however it remains relatively uncommon to be encountered in hospitals inside the UK. While the majority of cases encountered are mild, severe disease with jaundice and acute renal failure has been described, highlighting the importance of clinician awareness in non-endemic settings. We summarise the case of a 54-year-old male with a two-week history of malaise, fevers and oliguria who was initially treated for sepsis of unknown origin. The patient rapidly deteriorated and was admitted to ITU for haemofiltration whilst further investigations took place to establish a diagnosis.
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