Atypical Polypoid Bladder Lesion Mimicking Urothelial Carcinoma in a Young Male: A Case Report About a Possible Autoimmune-Triggered Granulomatous Inflammation With Secondary Colonization.

Severin P Hofmann, Uwe Bieri, Franz von Stauffenberg, Stefan Schneider, Gad Singer, Michael Greiner, Lukas John Hefermehl

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Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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0 citing papers in PubMed.

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5 · Who and what money

Authors and funding

7 authors.

Severin P HofmannDepartment of Urology, Kantonsspital Baden, Baden, CHE.

Uwe BieriDepartment of Urology, Kantonsspital Baden, Baden, CHE.

Franz von StauffenbergDepartment of Urology, Universitätsspital Zürich, Zurich, CHE.

Stefan SchneiderDepartment of Rheumathology, Rheumazentrum Aarau, Aarau, CHE.

Gad SingerDepartment of Pathology, Kantonsspital Baden, Baden, CHE.

Michael GreinerDepartment of Infectious Disease, Kantonsspital Baden, Baden, CHE.

Lukas John HefermehlDepartment of Urology, Kantonsspital Baden, Baden, CHE.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gross hematuria is a critical clinical symptom requiring thorough diagnostic evaluation, particularly due to its association with urothelial carcinoma. However, other differential diagnoses must also be considered, including renal carcinoma, infection, urolithiasis, and autoimmune disease. We report the case of a 28-year-old male presenting with gross hematuria, flank pain, and dysuria. Imaging revealed bladder wall thickening and bilateral narrowing of the renal pelvis. Cystoscopy showed a large, polypoid lesion suggestive of urothelial carcinoma. Transurethral resection (TUR-B) was performed; however, histological analysis revealed granulation tissue with inflammatory infiltrates, multinucleated giant cells, and necrosis but no evidence of malignancy. Metagenomic sequencing identified

Indexed as

gross hematuriamimicking urothelial carcinomapolypoid bladder lesionsecondary microbial colonizationvasculitis of the bladder

Identifiers

PMID41523444

DOI10.7759/cureus.98879

PMCPMC12784439

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