Evidence map›Paper›PMID 41523417›Full record

ArticleCureus2025

Unexpected Malignancy: Squamous Cell Carcinoma Arising in an Ovarian Mature Cystic Teratoma Diagnosed Postoperatively.

Chaimae Bekhakh, Anass Haloui, Mahmoud Aberkane, Nassira Karich, Amal Bennani

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chaimae BekhakhPathology Department, Mohammed VI University Hospital, Faculty of Medicine and Pharmacy, Mohammed First University, Oujda, MAR.
Anass HalouiPathology Department, Mohammed VI University Hospital, Faculty of Medicine and Pharmacy, Mohammed First University, Oujda, MAR.
Mahmoud AberkanePathology Department, Mohammed VI University Hospital, Faculty of Medicine and Pharmacy, Mohammed First University, Oujda, MAR.
Nassira KarichPathology Department, Mohammed VI University Hospital, Faculty of Medicine and Pharmacy, Mohammed First University, Oujda, MAR.
Amal BennaniPathology Department, Mohammed VI University Hospital, Faculty of Medicine and Pharmacy, Mohammed First University, Oujda, MAR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although mature cystic teratomas (MCTs) of the ovary are typically benign, their rare malignant transformation (MT) into squamous cell carcinoma (SCC) represents a diagnostic and therapeutic challenge. Preoperative imaging frequently misleads clinicians by suggesting a benign lesion, and the malignant component is usually identified only after histopathological evaluation. Reporting such cases is valuable to raise awareness of this unusual entity and to emphasize the need for vigilance in the management of ovarian teratomas, particularly in women beyond reproductive age. We report the case of a 65-year-old woman in whom imaging suggested a benign teratoma, but histology revealed SCC, underlining the diagnostic challenge and the importance of awareness of this rare but clinically significant transformation.

Indexed as

malignant transformationmature cystic teratomaovarian germ cell tumorovarysquamous cell carcinoma

Identifiers

PMID41523417
PMCPMC12780604

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.