ArticleThe Indian journal of radiology & imaging2026
Comparison of Dual-Energy CT Derived Myocardial Delayed Enhancement with Magnetic Resonance Imaging in Patients with Cardiomyopathy-Related Heart Failure.
Article in The Indian journal of radiology & imaging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Cardiomyopathy (CMP) related heart failure (HF) is a leading cause of disability and death. Using novel cardiac magnetic resonance imaging (CMRI), late gadolinium enhancement (LGE) is detected as an imaging marker of myocardial fibrosis. Over the last few years there is increased percentage of ischemia related heart failure, subjecting patients to invasive catheter angiography for detection of coronary artery disease (CAD). This study evaluates the role of Dual energy cardiac computed tomography (DECT) as a one-step modality to diagnose coronary artery disease and myocardial fibrosis in a single step investigation. Purpose: The aim of the study is to assess the diagnostic performance of DECT in the evaluation of myocardial delayed enhancement (MDE) with LGE MRI as the standard of reference. Materials and Methods: Thirty patients of heart failure with reduced ejection fraction (<40%) who were diagnosed with myocardial scar (LGE) on CMRI underwent DECT coronary angiography and delayed scan at 8 to 10 minutes for assessment of MDE, mainly assessing the coronary vascular status and the pattern of MDE detection. The MDE images (virtual monochromatic [VM] and iodine density maps) were compared with the LGE images, with LGE as the gold standard. Results: The diagnostic accuracy of iodine density map and VM images as compared with LGE in CMRI is 76 and 66%, respectively ( Conclusion: DECT angiography with MDE is a robust investigation to detect coronary artery disease and myocardial fibrosis in the same sitting with comparable performance when compared with CMRI-derived LGE imaging.
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